Laser endoureterotomy and endopyelotomy: an update

Emiliani, Esteban; Breda, Alberto

doi:10.1007/s00345-014-1405-3

Cited by 34 publications

(33 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ureteral stricture (US), defined as a narrowing of the ureter with urine flow obstruction, is a major concern in urology as renal function may be silently affected . Iatrogenic strictures after gynaecologic/urologic operations are the most common etiologies contributing to US, accounting for 35% incidence rates of all strictures .…”

Section: Introductionmentioning

confidence: 99%

Bone marrow mesenchymal stem cells reduce ureteral stricture formation in a rat model via the paracrine effect of extracellular vesicles

Luo

Zhao

Wang

et al. 2018

J Cellular Molecular Medi

View full text Add to dashboard Cite

With no effective therapy to prevent or treat ureteral stricture (US), a multifactorial fibrotic disease after iatrogenic injury of the ureter, the need for new therapies is urgent. Mesenchymal stem cells (MSCs) have been widely studied for treating tissue defects and excessive fibrosis, and recent studies established that one of the main therapeutic vectors of MSCs is comprised in their secretome and represented by extracellular vesicles (EVs). Thus, we have determined to explore the specific role of MSCs‐derived EVs (MSC‐EVs) treatment in a pre‐clinical model of US. The results firstly showed that either a bolus dose of MSCs or a bolus dose of MSC‐EVs (administration via renal‐arterial) significantly ameliorated ureteral fibrosis and recuperated ureter morphological development in a US rat model. We confirmed our observations through MSCs or MSC‐EVs treatment alleviated hydronephrosis, less renal dysfunction and blunted transforming growth factor‐β1 induced fibration. Due to MSC‐EVs are the equivalent dose of MSCs, and similar curative effects of transplantation of MSCs and MSC‐EVs were observed, we speculated the curative effect of MSCs in treating US might on account of the release of EVs through paracrine mechanisms. Our study demonstrated an innovative strategy to counteract ureteral stricture formation in a rat model of US.

show abstract

Section: Introductionmentioning

confidence: 99%

Bone marrow mesenchymal stem cells reduce ureteral stricture formation in a rat model via the paracrine effect of extracellular vesicles

Luo

Zhao

Wang

et al. 2018

J Cellular Molecular Medi

View full text Add to dashboard Cite

show abstract

“…Corcoran and colleagues have demonstrated the success of endoscopic treatment via balloon dilatation and/or laser endoureterotomy in their series of 75 patients. [15][16] Also Emiliani and colleagues found that laser endoureterotomy was successful with minimal perioperative morbidity. 16 Despite the reported success rates and low morbidities, endoscopic procedures require attention and a high level of expertise.…”

Section: Discussionmentioning

confidence: 99%

“…[15][16] Also Emiliani and colleagues found that laser endoureterotomy was successful with minimal perioperative morbidity. 16 Despite the reported success rates and low morbidities, endoscopic procedures require attention and a high level of expertise. As suggested by Traxer and colleagues, the ureteral integrity should be assessed at the end of each ureteroscopic procedure.…”

Section: Discussionmentioning

confidence: 99%

A guidewire introducer as a ureteral foreign body: A case report

Şener¹,

Cloutier²,

Audouin³

et al. 2015

CUAJ

View full text Add to dashboard Cite

A 63-year-old male, previously treated for a ureteral tumour by a right-sided segmental ureterectomy and end-to-end anastomosis of ureteral segments, was referred to our clinic for endoscopic follow-up. During his follow-up, he was diagnosed with partial right-sided ureteral stricture which eventually progressed to complete obstruction. During the ureteroscopy, as the stenotic segment did not allow passage of an hydrophilic guidewire, an antegraderetrograde approach was decided. On the antegrade endoscopic view, a near-complete stenosis was diagnosed and a nephrostomy catheter (12 Fr) was placed. A second intervention was planned and from the nephrostomy tract, the ureteroscope was placed into the right pyelocaliceal system. The diagnostic ureteroscopy revealed a foreign object proximal to the stenotic area. Right-sided segmental ureterectomy of the stenotic segment with ureteroneocystostomy and removal of the foreign object was performed. This is the only case in literature to reveal a guidewire introducer as a ureteral foreign body. This case also highlights the importance of the fragility of the ureter, the importance of the equipment, of always being watchful during a surgery, and the importance of checking the integrity of the equipment at the end of each procedure.

show abstract

“…The facts that stricture shouldn't be longer than 2 cm and the operated kidney should be free of stones should be taken into consideration during qualification for treatment. The incision should be made laterally, so as not to damage possible crossing vessels [ 49 , 56 ].…”

Section: Introductionmentioning

confidence: 99%

The role of lasers in modern urology

Dołowy¹,

Krajewski²,

Dembowski³

et al. 2015

CEJU

View full text Add to dashboard Cite

IntroductionThe functioning of modern urological departments and the high level of service they provide is possible through, among other things, the use of modern laser techniques.Material and methodsOpen operations have been replaced by minimally invasive procedures, and classical surgical tools by advanced lasers.The search for new applications with lasers began as technology developed. Among many devices available, holmium, diode and thulium lasers are currently the most popular.ResultsDepending on the wavelength, the absorption by water and hemoglobin and the depth of penetration, lasers can be used for coagulation, vaporization and enucleation. In many centres, after all the possibilities of pharmacological treatment have been exhausted, lasers are used as the primary treatment for patients with benign prostatic hyperplasia, with therapeutic results that are better than those obtained through open or endoscopic operations. The use of lasers in the treatment of urolithiasis, urinary strictures and bladder tumours has made treatment of older patients with multiple comorbidities safe, without further necessity to modify the anticoagulant drug treatment. Laser procedures are additionally less invasive, reduce hospitalization time and enable a shorter bladder catheterization time, sometimes even eliminating the need for bladder catherterization completely. Such procedures are also characterized by more stable outcomes and a lower number of reoperations.ConclusionsThere are also indications that with the increased competition among laser manufacturers, decreased purchase and maintenance costs, and increased operational safety, laser equipment will become mandatory and indispensable asset in all urology wards.

show abstract

Laser endoureterotomy and endopyelotomy: an update

Abstract: Laser endoureterotomy and endopyelotomy should be considered a reasonable treatment option in selected patients.

Cited by 34 publications

References 36 publications

Bone marrow mesenchymal stem cells reduce ureteral stricture formation in a rat model via the paracrine effect of extracellular vesicles

Bone marrow mesenchymal stem cells reduce ureteral stricture formation in a rat model via the paracrine effect of extracellular vesicles

A guidewire introducer as a ureteral foreign body: A case report

The role of lasers in modern urology

Contact Info

Product

Resources

About