Laser Doppler velocimetry and computer automation to measure low velocities in a pulmonary model

Experimental methods for flow and aerosol measurements in human airways and their replicas

“…These models are still frequently used, often geometrically truncated to a different extent. Some investigators applied even simpler models, such as the trivial Y-shape, to study lung flow in a single symmetrical bifurcation (Corieri and Riethmuller, 1989;Lieber and Zhao, 1998;Peattie and Schwarz, 1998). A more complex model comprising five generations of airways, made of straight hollow glass tubes, was used recently by Kerekes et al (2016).…”

“…(Adler and Brucker, 2007;Grosse et al, 2007), for PDA e.g. with an optical refractive index of about 1.41, glass (for LD methods: (Corcoran and Chigier, 2000;Corieri and Riethmuller, 1989) or acrylic plastic (Farag et al, 2000;Tanaka et al, 1999). Especially for 3D evaluation methods, the refractive index must be matched to a precision of 0.01 to guarantee adequate reconstruction of 3D PIV images from the planar images.…”

“…Especially for 3D evaluation methods, the refractive index must be matched to a precision of 0.01 to guarantee adequate reconstruction of 3D PIV images from the planar images. A mixture of water and glycerin with a mass ratio of 0.42:0.58 (water:glycerin) is typically used as working fluid here (PIV: (Adler and Brucker, 2007;Grosse et al, 2007;Janke and Bauer, 2016), LD: (Corieri and Riethmuller, 1989;Zhao and Lieber, 1994b), and others).…”

Research of transport and deposition of aerosol in human airway replica

“…Laser Doppler Velocimetry (LDV) method allows such measurements. Nevertheless the first LDV measurements were provided with glycerine by Corrieri and Riethmüller [8] in 1989 on highly idealized Y shape model. Y shaped models were used in 1998 also by Peatie and Schwarz [19] and in the same year by Lieber and Zhao [16].…”