Laser conization for microinvasive carcinoma of the cervix. Short-term results

Abstract

Thirty-one patients with microinvasive carcinoma of the uterine cervix (less than 3.0 mm invasion, no lymph vascular involvement), were treated with combination laser conization. The mean follow-up period was 36 months. No cases of invasive disease have been diagnosed during follow-up. Examination during follow-up revealed atypical columnar epithelium in one case, but the hysterectomy specimen was normal. Based on these short-term results, combination laser conization for microinvasive carcinoma of the cervix seemed a sufficient therapy. A precise and careful histopathologic evaluation, and the patient acceptance of a strict follow-up schedule are mandatory to a decision to employ conservative management of microinvasive cervical carcinoma. Only long-term follow-up in patients treated by conservative therapy will be able to finally justify this approach.

The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology

“…The SGO definition does not comment on the width of the lesion. Clinical studies and expert opinion have generally concluded that ''microinvasive'' SCC can be managed conservatively by cervical conization, LEEP excision, or simple hysterectomy, although more restrictive depth criteria of 2 mm or even 1 mm have been proposed or used [98,[100][101][102][103][104][105][106][107][108][109][110][111][112][113].…”