Laser-based in situ embedding of metal nanoparticles into bioextruded alginate hydrogel tubes enhances human endothelial cell adhesion

Blaeser, Andreas; Million, Nina; Campos, Daniela F. Duarte; Gamrad, Lisa; Köpf, Marius; Rehbock, Christoph; Nachev, Milen; Sures, Bernd; Barcikowski, Stephan; Fischer, Horst

doi:10.1007/s12274-016-1218-3

Cited by 38 publications

(53 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Controlling the flow rate of differently loaded, microfluidic channels connected to one nozzle allows the generation of single filaments with material properties displaying spatiotemporal variance [20]. Moreover, feeding different materials into the center and the annulus of a coaxial nozzle enables the printing of lines with a core-shell structure [21,22] and tubular filaments [23][24][25]. In laser-based bioprinting a pulsed laser beam is utilized to generate drops [6,33].…”

Section: Line-by-line Bioprintingmentioning

confidence: 99%

3D bioprinting of cell-laden hydrogels for advanced tissue engineering

Blaeser

Campos

Fischer

2017

Current Opinion in Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

Section: Line-by-line Bioprintingmentioning

confidence: 99%

3D bioprinting of cell-laden hydrogels for advanced tissue engineering

Blaeser

Campos

Fischer

2017

Current Opinion in Biomedical Engineering

Self Cite

View full text Add to dashboard Cite

“…A factor that is important for all of these different biomedical applications is the homogeneous distribution of nanoparticles within the polymer matrix [75]. This is crucial to ensure a uniform release of the metal ions and hence, strongly affects the composite properties [51,73,75], its influence on the cells and body tissue.…”

Section: Biomedicinementioning

confidence: 99%

“…This is crucial to ensure a uniform release of the metal ions and hence, strongly affects the composite properties [51,73,75], its influence on the cells and body tissue. In contrast, the application of PLAL produces nanoparticles of high purity.…”

Section: Biomedicinementioning

confidence: 99%

Process Chain for the Fabrication of Nanoparticle Polymer Composites by Laser Ablation Synthesis

2017

Self Cite

View full text Add to dashboard Cite

Nanoparticle polymer composites are of growing interest due to their unique properties. However, conventional composite synthesis methods usually require several process steps including steps for cleaning and improving the particlematrix dispersion. As an alternative, laser ablation synthesis can be used to prepare tunable composite materials. This method enables an easy process chain, without the need of additional steps. In this status report, the process chain of laser-based pre-series fabrication of nanocomposites is visualized, and the increase of the method's technology readiness level is demonstrated. The process steps are demonstrated from the synthesis of the colloid to applicable functional products. The advantages of using laser ablation for nanocomposite synthesis are highlighted.

show abstract

“…The method has a number of advantages such as the simple operation, the environmentally friendly process (without organic solvents and toxic heavy metal elements), the mild condition (in aqueous system at room temperature), and the convenient post‐treatment. In addition, the Mn‐doped ZnS QDs/alginate nanocomposite beads are composed of low toxic QDs and biocompatible alginate, which are beneficial for their subsequent applications …”

Section: Introductionmentioning

confidence: 98%

“…prepared biocompatible chitosan nanobeads encapsulating QDs and paramagnetic gadrinium diethylene triamine pentaacetate, which can be used as fluorescent biomarkers . Alginate, an anionic polysaccharide extracted from seaweeds, has attracted much attention in the biomedical field due to its attractive properties such as non‐toxicity, biocompatibility, and biodegradability . In particular, it has been reported that some divalent and multivalent cations (e.g., Ca 2+ , Ba 2+ , and Fe 3+ ) are able to bind to the G‐blocks of alginate, thereby inducing the gelation of alginate to form a gel .…”

Section: Introductionmentioning

confidence: 99%

Direct Generation of Mn‐Doped ZnS Quantum Dots/Alginate Nanocomposite Beads Based on Gelation and In Situ Synthesis of Quantum Dots

Chen

Lei

Wang

et al. 2019

Macro Materials & Eng

View full text Add to dashboard Cite

The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/mame.201800681. ZnS Quantum DotsHerein, a concise and novel method is developed to directly generate Mndoped ZnS QDs/alginate nanocomposite beads. In this method, the ionic gelation of alginate is employed to produce alginate gel beads in a solution of Zn 2+ and Mn 2+ ions. Subsequently, the gel beads serve as the reaction support for in situ synthesis of Mn-doped ZnS QDs in the beads through the reaction of sodium sulfide with Zn 2+ and Mn 2+ ions. The method has many benefits such as the simple preparation, the environmentally friendly process, the mild conditions, and the easy post-treatment for the beads. The resulting QDs/alginate beads are homogeneous and stable gel spheres which show clear fluorescence. TEM images demonstrate that Mn-doped ZnS QDs are homogeneously distributed within the QDs/alginate nanocomposite, and their average size is 2.4 ± 0.3 nm. Potentially, the QDs/alginate beads can be utilized for fluorescence bioimaging, as well as fluorescence detection toward metal ions.

show abstract

Laser-based in situ embedding of metal nanoparticles into bioextruded alginate hydrogel tubes enhances human endothelial cell adhesion

Cited by 38 publications

References 64 publications

3D bioprinting of cell-laden hydrogels for advanced tissue engineering

3D bioprinting of cell-laden hydrogels for advanced tissue engineering

Process Chain for the Fabrication of Nanoparticle Polymer Composites by Laser Ablation Synthesis

Direct Generation of Mn‐Doped ZnS Quantum Dots/Alginate Nanocomposite Beads Based on Gelation and In Situ Synthesis of Quantum Dots

Contact Info

Product

Resources

About