Laser-assisted nanoceramics reinforced polymer scaffolds for tissue engineering: additional heating and stem cells behavior

Shishkovsky, Igor; Scherbakov, V. I.; Volchkov, Vladislav; Волова, Л. Т.

doi:10.1117/12.2290583

Cited by 5 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Miniature samples of the 3D printed nCPM with a crosssectional area of 6 mm 2 and a base length of 3 mm were used for tensile strength testing. Thermal stabilization of the samples was performed before testing [26]. Tests with heating were necessary to identify the limiting changes in the strength and deformation properties under the forced operating conditions of the 3D printed metamaterials.…”

Section: Resultsmentioning

confidence: 99%

“…Finally, the cell morphology, proliferative activity, and adhesion of multipotent mesenchymal stromal cells (MMSCs) to 3D biocompatible nCPM-based tissue-engineering scaffolds were realized at the Samara Clinical Center for Cellular Technologies (Doctor of Medicine, PhD Volchkov S V) [25][26][27]. Materials with cells attached to them were stained with DAPI nuclear fluorescent dye (Life Technologies, USA) and evaluated by their fluorescent presence under an Axiovision A1 optical microscope (Carl Zeiss, Germany) at a wavelength of 420 nm.…”

Section: Materials and Equipmentmentioning

confidence: 99%

See 1 more Smart Citation

Additive manufacturing of polymer composites with nano-titania inclusions

Shishkovsky

Scherbakov

2021

Laser Phys. Lett.

View full text Add to dashboard Cite

This study focuses on the possibility of controlling the morphology, phase-structural transformations, shape and mechanical features of a nano ceramic-polymer matrix by adding nano-titanium dioxide (TiO2) to the polymer during a selective laser sintering process. 3D parts were manufcatured from dissimilar polymers and nano-titania powder compositions with different volume ratios. Evaluations of the microstructural characteristics of the 3D samples were performed using optical and scanning electron microscopy (SEM) and x-ray analysis. SEM indicated a heterogeneous distribution of nano-titania in the polymer matrix. The x-ray patterns confirmed the presence of the original phase (TiO2) with some changes, which is useful for biomedical applications. Heating the 3D parts for approximately 30 additional minutes in the oven in the range of 50 °C–250 °C allowed us to reveal the conditions necessary for changing the porosity of the ceramic–polymer matrix, without requiring a polymer binder or titania framework fixing.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Materials and Equipmentmentioning

confidence: 99%

Additive manufacturing of polymer composites with nano-titania inclusions

Shishkovsky

Scherbakov

2021

Laser Phys. Lett.

View full text Add to dashboard Cite

show abstract

“…SLS technology uses a high-powered laser beam to sinter/fire the ceramics at an elevated temperature. The laser is aimed at specific areas of the aggregate powdered particles using the distribution to create solid objects [31][32][33]. The SLM is principally similar to SLS; however, SLM completely melts and fuses the powder particles using a high-powered laser beam to form a solid object [34,35].…”

Section: Selective Laser Sintering/melting (Sls/slm)mentioning

confidence: 99%

“…Therefore, many researchers sought to address these issues by integrating nanoparticles into the liquid binder. Recently Huang et al [32] studied the use of an inorganic colloidal binder (decomposable binder) as a binding agent for the construction of 3Y-ZrO 2 ceramic structures using BJ technology. They selected zirconium basic carbonate as a precursor, and it was dispersed in the colloidal solvent to produce decomposable inorganic colloidal binder because it can be easily decomposed upon sintering and can form zirconia 3D parts with no residue [48].…”

Section: Binder Jetting (Bj)mentioning

confidence: 99%

“…It was established that the inorganic colloidal binder-based zirconia scaffolds exhibited superior surface quality and density compared to the conventional polymer binder. Conversely, Zhao et al [32] ***attempted to print zirconia samples using a liquid binder containing zirconia nanoparticles (10 wt%). The density was increased by approximately 86.8%, whereas shrinkage was reduced by approximately 10.6% after sintering the printed parts [51].…”

Section: Binder Jetting (Bj)mentioning

confidence: 99%

See 1 more Smart Citation

Perspective Chapter: Additive Manufactured Zirconia-Based Bio-Ceramics for Biomedical Applications

Sakthiabirami¹,

Vaiyapuri²,

Kang³

et al. 2022

Advanced Additive Manufacturing

View full text Add to dashboard Cite

Zirconia was established as one of the chief vital ceramic materials for its superior mechanical permanency and biocompatibility, which make it a popular material for dental and orthopedic applications. This has inspired biomedical engineers to exploit zirconia-based bioceramics for dental restorations and repair of load-bearing bone defects caused by cancer, arthritis, and trauma. Additive manufacturing (AM) is being promoted as a possible technique for mimicking the complex architecture of human tissues, and advancements reported in the recent past make it a suitable choice for clinical applications. AM is a bottom-up approach that can offer a high resolution to 3D printed zirconia-based bioceramics for implants, prostheses, and scaffold manufacturing. Substantial research has been initiated worldwide on a large scale for reformatting and optimizing zirconia bioceramics for biomedical applications to maximize the clinical potential of AM. This book chapter provides a comprehensive summary of zirconia-based bioceramics using AM techniques for biomedical applications and highlights the challenges related to AM of zirconia.

show abstract