Laser-Assisted Facial Contouring Using a Thermally Confined 1444-nm Nd-YAG Laser: A New Paradigm for Facial Sculpting and Rejuvenation

Holcomb, J. David; Turk, Jon B.; Baek, Sung-Jong; Rousso, Daniel E.

doi:10.1055/s-0031-1283051

Cited by 19 publications

(30 citation statements)

References 34 publications

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“…A novel Nd:YAG device that emits energy at a wavelength of 1,444 nm has recently been developed; this wavelength is more highly absorbed by adipose tissue and water than other wavelengths currently available [8]. Only a few studies have investigated whether the 1,444-nm Nd:YAG laser enables localized lipolysis of discrete structures within the body and facial regions [9,10]. To the best of our knowledge, this article is one of the first to report the use of 1,444-nm Nd:YAG LAL for gynecomastia.…”

Section: Introductionmentioning

confidence: 99%

Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study

Yoo

Bae²,

Won

et al. 2015

Dermatology

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Background: Laser-assisted liposuction (LAL) is currently widely used to reduce localized fat. A novel Nd:YAG laser that uses a wavelength of 1,444 nm, which is better absorbed by fat, has recently been introduced. In this study, we investigated the efficacy of 1,444-nm Nd:YAG LAL for the treatment of gynecomastia. Patients and Methods: Thirteen Korean male patients (20-28 years, mean age 23 years) diagnosed with gynecomastia were enrolled in this study. All patients were treated by LAL with 1,444-nm Nd:YAG laser (100 µs pulse width, 40 Hz frequency, 300 mJ pulse energy and 12 W power with continuous emission) after tumescent anesthetic infiltration and were then evaluated. Outcome was assessed using the following 4 methods: (1) clinical assessment with photographs obtained before and 12 weeks after LAL treatment, (2) comparison of pre- and postoperative patient chest circumferences, (3) computed tomography (CT) scans to evaluate changes in breast thickness and (4) a patient satisfaction survey at the end of the study. Results: After 12 weeks, most patients (84.5%) showed an improvement greater than 50%. Mean chest circumference was significantly reduced from 109.6 ± 8.2 to 101.2 ± 4.4 cm 12 weeks after LAL (p < 0.001). CT scans showed a significant reduction in mean breast thickness from 22.7 ± 3.2 to 15.6 ± 2.4 mm (p = 0.016). Side effects (pain, edema, numbness and ecchymosis) were minimal and disappeared shortly after the first manifestation. Conclusion: Gynecomastia can be safely treated with 1,444-nm Nd:YAG LAL to reduce fatty tissue and total breast volume.

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Section: Introductionmentioning

confidence: 99%

Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study

Yoo

Bae²,

Won

et al. 2015

Dermatology

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“…In some scenarios, greater thermal confinement and a corresponding limitation of the potential for unintended collateral thermal injury may be of clinical benefit during laser lipolysis [16]. Significant collateral thermal injury may not be likely during laser lipolysis-assisted body contouring where there may be large volumes of target tissue and where vital structures may be relatively distant.…”

Section: Discussionmentioning

confidence: 99%

“…In contrast, the potential for undesirable collateral thermal injury is likely much higher during laser lipolysis-assisted contouring of facial structures (e.g. melolabial folds, jowls) where target tissue volumes are much smaller and where delicate structures are anatomically proximate [16]. …”

Section: Discussionmentioning

confidence: 99%

“…While the authors recognize certain limitations in data relevance across species, in practice, the thermodynamic characteristics of the micropulsed (100 μs) 1,444 nm Nd:YAG laser have enabled safe targeting of small volumes of fat in areas where tissues are delicate and the likelihood of undesirable secondary collateral thermal injury might otherwise be high (eg, facial areas including mid- and lower face) [16]. …”

Section: Discussionmentioning

confidence: 99%

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Ablation efficiency and relative thermal confinement measurements using wavelengths 1,064, 1,320, and 1,444 nm for laser-assisted lipolysis

Youn

Holcomb²

2012

Lasers Med Sci

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Laser-assisted lipolysis is routinely used for contouring the body and the neck while modifications of the technique have recently been advocated for facial contouring. In this study, wavelength-dependence measurements of laser lipolysis effect were performed using different lasers at 1,064, 1,320, and 1,444 nm wavelengths that are currently used clinically. Fresh porcine skin with fatty tissue was used for the experiments with radiant exposure of 5–8 W with the same parameters (beam diameter = 600 μm, peak power = 200 mJ, and pulse rate = 40 Hz) for 1,064, 1,320 and 1,444 nm laser wavelengths. After laser irradiation, ablation crater depth and width and tissue mass loss were measured using spectral optical coherence tomography and a micro-analytical balance, respectively. In addition, thermal temporal monitoring was performed with a thermal imaging camera placed over ex vivo porcine fat tissue; temperature changes were recorded for each wavelength. This study demonstrated greatest ablation crater depth and width and mass removal in fatty tissue at the 1,444 nm wavelength followed by, in order, 1,320 and 1,064 nm. In the evaluation of heat distribution at different wavelengths, reduced heat diffusion was observed at 1,444 nm. The ablation efficiency was found to be dependent upon wavelength, and the 1,444 nm wavelength was found to provide both the highest efficiency for fatty tissue ablation and the greatest thermal confinement.

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“…Laser lipolysis has many advantages, including less bleeding, pain, recovery time and tissue damage than other liposuction methods. In addition, by the removal of fat tissues, laser lipolysis has a skin tightening effect by heating the dermal and subdermal tissues . The heating of the deep dermis induces an inflammation process.…”

Section: Introductionmentioning

confidence: 99%

Histological evaluation of dermal tissue remodeling with the 1444‐nm neodymium:yttrium–aluminum–garnet laser in in vivo model

Kim

Min

Heo

et al. 2013

The Journal of Dermatology

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Laser lipolysis has a skin tightening effect by heating the deep dermis, in addition to the removal of fat tissues. The 1444-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has been expected to be more effective and safe for laser lipolysis, due to higher affinity to fat and water, than 1064-nm and 1320-nm wavelengths. The purpose of this study was to evaluate the skin tightening effect of the 1444-nm Nd:YAG laser through in vivo guinea pig models. The 1444-nm Nd:YAG laser was used to irradiate shaved dorsal skin of the guinea pigs and compared with controls (no power, only tunneling). Immediately, 1 week, 1 month and 3 months after laser administration, full-thickness skins were harvested and to evaluate dermal thickness, collagen organization, fibroblast proliferation, and intensity of elastic fibers and mucopolysaccharides, using hematoxylin-eosin, Masson-trichrome, Verhoeff's stain and Alcian blue stain. Dermal thickness showed an increase with time in all groups. In collagen organization, fibroblast proliferation, and intensity of elastic fibers and mucopolysaccharides, the treatment groups were higher than those of the control group, overall. Our study showed that the 1444-nm Nd:YAG laser appeared to be effective for the skin tightening effect in in vivo guinea pig models. The 1444-nm Nd:YAG laser can be used for skin tightening, as well as reduction of fat tissues.

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Laser-Assisted Facial Contouring Using a Thermally Confined 1444-nm Nd-YAG Laser: A New Paradigm for Facial Sculpting and Rejuvenation

Cited by 19 publications

References 34 publications

Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study

Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study

Ablation efficiency and relative thermal confinement measurements using wavelengths 1,064, 1,320, and 1,444 nm for laser-assisted lipolysis

Histological evaluation of dermal tissue remodeling with the 1444‐nm neodymium:yttrium–aluminum–garnet laser in in vivo model

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