Laser-Assisted Diagnostics

Development of a new approach to diagnosis of the early fluorosis forms by means of FTIR and Raman microspectroscopy

“…This requires the development of a diagnostic technique for the enamel condition to register changes in the enamel matrix during the development of fluorosis [17][18][19] . Early diagnosis of dental diseases using precision monitoring methods is www.nature.com/scientificreports/ a key paradigm for ensuring public 15,[20][21][22][23][24] , hence the diagnosis of this disease at different levels of development is a priority scientific direction in therapeutic dentistry in the developed countries. Since the condition of human teeth is determined by changes occurring in the phase composition of the tissue at the micro and nano level, the use of spectroscopic methods of molecular identification is the most promising and sensitive tool to precisely assess such changes in the dental enamel [24][25][26] .…”

“…Early diagnosis of dental diseases using precision monitoring methods is www.nature.com/scientificreports/ a key paradigm for ensuring public 15,[20][21][22][23][24] , hence the diagnosis of this disease at different levels of development is a priority scientific direction in therapeutic dentistry in the developed countries. Since the condition of human teeth is determined by changes occurring in the phase composition of the tissue at the micro and nano level, the use of spectroscopic methods of molecular identification is the most promising and sensitive tool to precisely assess such changes in the dental enamel [24][25][26] . Raman spectroscopy is most often used for diagnostics of dental diseases as a non-destructive method of analysis, which allows to obtain direct data regarding the local atomic structure, chemical and molecular composition of biological objects 18,20,24,[27][28][29] .…”

“…Since the condition of human teeth is determined by changes occurring in the phase composition of the tissue at the micro and nano level, the use of spectroscopic methods of molecular identification is the most promising and sensitive tool to precisely assess such changes in the dental enamel [24][25][26] . Raman spectroscopy is most often used for diagnostics of dental diseases as a non-destructive method of analysis, which allows to obtain direct data regarding the local atomic structure, chemical and molecular composition of biological objects 18,20,24,[27][28][29] . Also, the hard tissue of a human tooth can be investigated by infrared spectroscopy methods [30][31][32][33][34] , which due to minimal external influences, has not been modified by the method 35 .…”

“…This requires the development of a diagnostic technique for the enamel condition to register changes in the enamel matrix during the development of fluorosis 17 – 19 . Early diagnosis of dental diseases using precision monitoring methods is a key paradigm for ensuring public 15 , 20 – 24 , hence the diagnosis of this disease at different levels of development is a priority scientific direction in therapeutic dentistry in the developed countries.…”

Development of a Visualisation Approach for Analysing Incipient and Clinically Unrecorded Enamel Fissure Caries Using Laser-Induced Contrast Imaging, MicroRaman Spectroscopy and Biomimetic Composites: A Pilot Study

“…The use of different wavelengths can detect differences in the density, structure and chemical composition of the biological tissue, while fluorescence losses are appropriate for assessing the stage and depth of the caries infection [ 12 , 24 ]. Currently, approaches to caries visualisation based on the fluorescence of the intact and carious tissue assist dentists in providing minimally invasive treatment; moreover, they can do so without X-ray analysis [ 28 , 30 , 31 , 32 , 33 ], which can be inefficient, particularly when it is impossible to diagnose an incipient lesion and the destruction of tooth enamel in fissure system [ 26 , 30 , 33 ].…”