Laser Ablation of Biomaterials

Abstract

Abstract"iomaterials, deined by high biocompatibility and biodegradability, are intensively used in medical applications, mainly to replace partial or total, damaged or destroyed hard or soft tissues. Most of them are used not only as coatings for implant coverage but also as parts for some medical devices. In the last decades, researchers sought to ind the optimum processing methods and parameters to modify or deposit the biomaterial of interest. "n important family of techniques, used to process a biomaterial, is represented by laser techniques, based upon laser ablation phenomenon. Laser ablation of biomaterials ensures the transference or modiication with good precision and without or with minimal disruptions generated. To obtain thin coatings from biomaterials, one can use deposition techniques: pulsed laser deposition (PLD) or matrix-assisted pulsed laser evaporation (M"PLE). These techniques are chosen according to the selected biomaterial and desired performances of the obtained coating. Therefore, some sensitive biomaterials can be transferred only by M"PLE. Some results in the ield of calcium phosphates deposited by PLD or M"PLE are presented, proving the usefulness of these biomaterials for medical applications.

Laser Processed Antimicrobial Nanocomposite Based on Polyaniline Grafted Lignin Loaded with Gentamicin-Functionalized Magnetite

“…In this context, composite coatings based on an intrinsic conductive polymer (polyaniline grafted lignin, PANI-LIG), embedded with magnetite nanoparticles (Fe 3 O 4 ) and loaded with aminoglycoside antibiotic molecules (Gentamicin sulfate, GS), were deposited by the matrix assisted pulsed laser evaporation (MAPLE) technique, to examine their potential as electrically and magnetically controlled drug delivery platforms. The effectiveness of the selected laser processing method is dictated by the patterning facility for depositing on different geometric shapes of substrates in a highly uniform manner [ 3 ], the possibility to obtain multilayers or composite coatings [ 4 ], and a convenient transfer of a wide range of biomaterials [ 5 , 6 ]. Another important advantage of the MAPLE process consists in the elimination of major sources of contamination, proving to be a non-contact processing method suitable for specific medical applications [ 7 ].…”