Laser ablation inductively coupled plasma mass spectrometry—current shortcomings, practical suggestions for improving performance, and experiments to guide future development

García, Carmen C.; Lindner, Helmut; Niemax, K.

doi:10.1039/b813124b

Cited by 100 publications

(88 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering the above-mentioned heterogeneity and size structure of aerosols emerging from the LA process, indispensable pre-conditions for accurate analyses are (1) a representative aerosol composition, (2) high transport efficiencies, and (3) a complete decomposition of particles that reach the ICP. 9 For the purpose of representative sampling, Nd:YAG laser sources emitting nanosecond (ns) pulses (5 to 10 ns) in the mid-and far-ultraviolet (UV) spectral range down to 213 nm have been most commonly used. However, the formation of particles in the micrometer-size range produced this way has been reported to strongly affect precision and accuracy of Nd:YAG laser-based LA-ICP-MS analyses since they were found to insufficiently evaporate in the ICP, resulting in spikes and drifting signals.…”

Section: Fundamentalsmentioning

confidence: 99%

Review of the State-of-the-Art of Laser Ablation Inductively Coupled Plasma Mass Spectrometry

2011

View full text Add to dashboard Cite

This paper is a review of the basic principles and recent developments of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) as a method for the element-and isotope-selective trace analysis of solid materials. In the course of this review, the aerosol formation/transportation process, quantification issues, as well as technical aspects concerning the system configuration and ICP operating conditions are outlined. Furthermore, the performance of femtosecond (fs) LA-based analyses as one of the most important advancements made over the past years is discussed. The benefits offered by fs-LA in comparison to LA using nanosecond (ns) laser sources are demonstrated on the basis of oxide layer and silicate glass analyses with different applied calibration strategies.

show abstract

Section: Fundamentalsmentioning

confidence: 99%

Review of the State-of-the-Art of Laser Ablation Inductively Coupled Plasma Mass Spectrometry

2011

View full text Add to dashboard Cite

show abstract

“…Hirata [112] used a chemically assisted laser ablation technique (a Freon R-134a gas was introduced into the ablation cell as a fluorination reactant) to minimize the elemental fractionation. In addition, the energy density of the laser must be maintained at a sufficiently high and stable level; elemental fractionation in both ns-and fs-laser ablation systems can be reduced if the laser energy density exceeds the ablation threshold of the material being analyzed [113]. Furthermore, the ICP analytical conditions need to be optimized to achieve an improved degree of atomization and ionization (and thus a reduction in the degree of elemental fractionation), which can be monitored by the U + /Th + signal ratio in SRM 610 glass [105].…”

Section: Elemental Fractionation In Ablation Transport and Excitatiomentioning

confidence: 99%

Applications of LA-ICP-MS in the elemental analyses of geological samples

Liu

et al. 2013

Chin. Sci. Bull.

103

View full text Add to dashboard Cite

Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS), which is a rapidly developing analytical technique for the analyses of trace elements and isotopes, plays an important role in advancing the study of Earth science, especially with respect to micro-geochemistry. This article reviews the application of LA-ICP-MS in the elemental analysis of solid geological samples. Although LA-ICP-MS has been widely used in the spatial resolution analysis of element compositions and rapid bulk analysis of whole-rock and soil samples, the analysis accuracy is restricted by numerous factors, including the instrumental conditions, the elemental fractionation and matrix effects, the lack of sufficient matrix-matched reference materials, and the strategies for quantitative calibration and sensitivity drift correction. According to the type of samples and the analyte elements, the analysis accuracy can be improved through the optimization of instrument conditions and the adoption of suitable correction strategies and reference materials. LA-ICP-MS, geological sample, elemental analysis, quantitative strategy Citation:Liu Y S, Hu Z C, Li M, et al. Applications of LA-ICP-MS in the elemental analyses of geological samples.

show abstract

“…In this sense, past research investigated the laser ablation process itself, the composition and the size-distribution of laser-induced particles, the reduction of elemental fractionation effects, and also the particle transport to the ICP (see the survey articles ref. 8,9 and references therein). The overall transport efficiency in fslaser ablation was found to be more than 80% for different ablation cells using helium or argon as transport gas.…”

mentioning

confidence: 99%

Numerical simulation analysis of flow patterns and particle transport in the HEAD laser ablation cell with respect to inductively coupled plasma spectrometry

Lindner

Autrique

Pisonero

et al. 2010

J. Anal. At. Spectrom.

Self Cite

View full text Add to dashboard Cite

The present study analyses a specific laser ablation cell, the High Efficiency Aerosol Dispersion (HEAD) cell (see J. Pisonero et al., J. Anal. At. Spectrom., 2006, 21, 922-931), by means of computational fluid dynamics (CFD) simulations. However, this cell consists of different modular parts, therefore, the results are probably of interest for the further development of other ablation cells. In the HEAD cell, the ablation spot is positioned below an orifice in the ceiling of the sample chamber. The particle transport through this orifice has been analysed for a ceiling height of 0.8 mm. The critical velocity for the onset of particle losses was found to be independent on the ejection angle at the crater spot. The deceleration of the particles can be described as the stopping in an effectively steady gas. Particle losses were negligible in this modular part of the cell at the evaluated laser ablation conditions. The transport efficiency through the Venturi chamber was investigated for different sample gas flow rates. In this case, it was found that small particles were predominantly lost at low flow rates, the large particles at higher flow rates. Making use of the simulation results, it was possible to design a modification of the HEAD cell that results in extremely short calculated washout times. The simulations yielded a signal of less than 10 ms, which was produced by more than 99% of the introduced mass.

show abstract

Laser ablation inductively coupled plasma mass spectrometry—current shortcomings, practical suggestions for improving performance, and experiments to guide future development

Abstract: Niemax et al. LA-ICP-MS-current shortcomings, practical suggestions for improving performance, and experiments to guide future development Weiss et al. Towards a catalogue of glow discharge emission spectra

Cited by 100 publications

References 54 publications

Review of the State-of-the-Art of Laser Ablation Inductively Coupled Plasma Mass Spectrometry

Review of the State-of-the-Art of Laser Ablation Inductively Coupled Plasma Mass Spectrometry

Applications of LA-ICP-MS in the elemental analyses of geological samples

Numerical simulation analysis of flow patterns and particle transport in the HEAD laser ablation cell with respect to inductively coupled plasma spectrometry

Contact Info

Product

Resources

About