Laryngopharyngeal symptoms in patients with asthma: a cross‐sectional controlled study

Abstract

Laryngopharyngeal reflux disease is more prevalent and more severe in patients with asthma vs controls.

Laryngopharyngeal reflux disease, prevalence and clinical characteristics in ENT department of a tertiary hospital Tanzania

“…The most observed clinical signs among LPRD patient were thick endolaryngeal mucus followed by Vocal cord edema and partial ventricular obliteration with 90.9%, 88.6% and 72.7% respectively. These findings are similar to those reported by other authors 15,25,26 ; the least observed signs were granuloma formation and posterior commissure hypertrophy with 11.4%. similar to the findings by other studies 16,25 but contrary to Belafsk and Koufman in their study on validity and reliability of RFS who found posterior pharyngeal hypertrophy to be the most common observed laryngoscopic sign.…”

“…The study constituted 256 clients; Gender was well balanced with males 51.2% vs. females 48.8% with no statistical difference in LPRD between the two sexes, this was similarly with the findings from other studies. 14,15 Few other studies have found LPRD prevalence to be higher in female. 16 The differences may be due to different diagnostic tool and methodology used by different investigators.…”

“…From this study, most reported symptoms by clients diagnosed with LPRD were Globus sensation followed by hoarseness of voice and excessive urge to clear throat with 95.7%, 88.1% and 83.0% respectively; this was similar to other studies. 15,17,24 while the least reported ones were chronic cough, sore throat and difficult in swallowing with 31.9%, 23.4% and 14.9% respectively. The association between LPRD and hoarseness of voice was statistically significant; P Z 0.030.…”

“…27 The differences in pattern of risk factors may be attributed by different cultures, geographical locations and social behaviours of the study populations however high BMI was strongly associated with LPRD and statistically significant (P Z 0.012) this was similar to the findings in other studies. 15,28 It has been evidenced from various studies that as high as 41.8% of patients with LPRD are suffering from other conditions like Cardiovascular, gastrointestinal, musculoskeletal, respiratory and endocrine diseases. 29 This study found strong correlation between LPRD and diabetes mellitus type 2 and hypertension this finding is similar to other studies.…”

Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study

“…Laryngopharyngeal reflux (LPR) represents an extra-esophageal manifestation of GERD. The reflux of gastric contents is fundamental in both LPR and GERD, but the mechanism and the symptoms of the disorders are distinct [ 13 – 15 ]. LPR occurs when gastric contents pass the upper esophageal sphincter and usually occurs during daytime in the upright position, while GERD occurs when gastric contents pass the lower esophageal sphincter and takes place more often in the supine position at night-time or during sleep [ 16 ].…”