Laryngopharyngeal Reflux in Hypertrophic Laryngeal Diseases

Han, Honglei; Lyu, Qiuping; Zhao, Jianhui

doi:10.1177/0145561320953232

Cited by 5 publications

(3 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Changes in RSI can be seen in patients with chronic tobacco use, asthma, and underlying laryngeal pathologies, such as glottic insufficiency, vocal polyps, and malignancy. 15,16 These confounders were not excluded in this patient cohort, therefore although this study focuses on symptoms attributed to LPR, it draws a larger perspective on overall upper airway inflammation between race and insurance status.…”

Section: Discussionmentioning

confidence: 99%

Laryngopharyngeal Reflux: Effect of Race and Insurance Status on Symptomology

Varelas

Houser

Husain

2022

Ann Otol Rhinol Laryngol

View full text Add to dashboard Cite

Objectives: Laryngopharyngeal reflux (LPR) is an extraesophageal variant of gastroesophageal reflux disease associated with intermittent dysphonia, throat-clearing, and chronic cough. This study aims to evaluate the impact of race and insurance status on symptoms often attributable to LPR. Methods: Retrospective review of all patients with suspected LPR from 2017 to 2019 was performed at a tertiary care center. The diagnostic criteria comprised evaluation by a fellowship trained laryngologist and Reflux Symptom Index (RSI) scores. Demographics, patient history, and insurance status were recorded. Descriptive statistics were calculated for each parameter using SPSS version 22. Results: A total of 170 patients (96 White, 44 Black, 26 Latinx, 4 Asian) were included in this study. About 57.1% had private insurance, 30.6% had Medicare, and 11.8% had Medicaid. Black and Latinx patients demonstrated higher RSI scores (26.67 ± 8.61, P = .017) when compared to their White and Asian counterparts. RSI scores between all 3 insurance types also varied significantly ( P = .035). Medicaid patients reported higher RSI scores (28.65 ± 10.09, P = .028), while private insurance patients reported significantly lower scores (23.75 ± 7.88, P = .03). Controlling for insurance type eliminates the statistically significant association between RSI scores and Black and Latinx patients. Particularly, within the Medicaid group, Black, Latinx, and White patients did not have statistically different RSI scores. Conclusions: Black and Latinx patients presented with higher RSI scores than White and Asian patients. Similarly, Medicaid patients reported higher RSI scores than the Non-Medicaid cohort. These findings suggest that access to appropriate healthcare, due to varied insurance coverage and socioeconomic, may potentially influence symptoms attributed to LPR.

show abstract

Section: Discussionmentioning

confidence: 99%

Laryngopharyngeal Reflux: Effect of Race and Insurance Status on Symptomology

Varelas

Houser

Husain

2022

Ann Otol Rhinol Laryngol

View full text Add to dashboard Cite

show abstract

“…Severe LPR significantly impairs the quality of life and interferes with patients’ daily tasks and personal activities. Life-threatening LPR is present in patients with airway obstruction ( 6 , 7 ).…”

Section: Introductionmentioning

confidence: 99%

The Impact of Nutrition on the Onset, Course of the Disease and Quality of Life of Patients with Laryngopharyngeal Reflux

Prpić,

Peček Prpić,

Mendeš

et al. 2023

Food Technol. Biotechnol. (Online)

View full text Add to dashboard Cite

Research background. The role of dietary habits in patients with laryngopharyngeal reflux disease (LPR) is comparatively underexplored. The aim of the study is to examine dietary habits, onset and course of the disease as well as the quality of life of patients with LPR. Experimental approach. The results of the modified food frequency questionnaire (FFQ-m) and Laryngopharyngeal Reflux Health-Related Quality of Life (LPR-HRQL) questionnaires were compared between subjects with and without LPR. There were a total of 100 subjects with LPR and 65 subjects in the control group. The group of subjects with LPR was further randomly divided into two subgroups; the first subgroup was treated with esomeprazole in a twice daily dose of 20 mg combined with dietary and general lifestyle changes instructions, and the other with pantoprazole in a twice-daily dose of 20 mg combined with dietary and general lifestyle changes instructions. Participants were instructed to fill out FFQ-m and LPR-HRQL questionnaires immediately after the initial examination and then after control examinations that were 30 and 60 days after the initial examination. Results and conclusions. Patients with LPR consume more food with high reflux potential, drink more carbonated drinks and juices, and have a worse quality of life compared to the control group (p<0.001). Proton pump inhibitors in a twice-daily dose of 20 mg with a change in dietary habits, such as avoiding acidic, spicy, fermented, sweet, and fried foods same as other foods with a high reflux potential as well as carbonated drinks and juices with the introduction of foods with a low reflux potential and water significantly reduces symptoms of LPR and increases the quality of life (p<0.001). Novelty and scientific contribution. This is the first study showing the connection between dietary habits and quality of life in patients with LPR. The contribution of this research is an objective review of the follow-up of patients with LPR that could be used in their regular assessment.

show abstract

“… 4 The association between LPR and laryngeal carcinoma seems to be emerging. 5 , 6 Lifestyle modifications, such as weight loss, stopping tobacco/alcohol use, and refraining from lying down within three hours after dinner, can reduce LPRD. 7 Medications, including histamine-2 receptor antagonists and proton pump inhibitors, can help suppress acid production.…”

Section: Introductionmentioning

confidence: 99%