Laryngopharyngeal reflux and dysphagia in patients with obstructive sleep apnea: is there an association?

Caparroz, Fábio de Azevedo; Campanholo, Milena de Almeida Torres; Stefanini, Renato; Vidigal, Tatiana de Aguiar; Haddad, Leonardo; Bittencourt, Lia Rita Azeredo; Tufik, Sérgio; Haddad, Fernanda Louise Martinho

doi:10.1007/s11325-019-01844-0

Cited by 14 publications

(18 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two studies reported no significant correlation of severity of OSAS and presence of dysphagia but found increased incidence of dysphagia in older individuals as compared with younger OSAS [22,23]. Further, one study in the literature found no significant differences in gender for presence of dysphagia [22] whereas another study found significant difference among gender [48]. In addition, surgical treatments and dysphagia is another important risk factor to be considered [19,20] Thus, a potential future research direction would be to investigate the relationships of potential factors, such as age, comorbidities, BMI, severity of OSAS, and AHI scores, that may increase the risk of dysphagia in patients with OSAS.…”

Section: Discussionmentioning

confidence: 98%

“…An additional factor to be considered is laryngopharyngeal reflux (LPR). Caparroz and colleagues studied the association of dysphagia and LPR in patients with moderate/severe OSAS [48]. The investigators reported the prevalence of dysphagia and LPR to be 27.3%, and 59.7%, respectively [48].…”

Section: Discussionmentioning

confidence: 99%

“…Caparroz and colleagues studied the association of dysphagia and LPR in patients with moderate/severe OSAS [48]. The investigators reported the prevalence of dysphagia and LPR to be 27.3%, and 59.7%, respectively [48]. The presence of both dysphagia and LPR was reported to be approximately 18% in patients with OSAS; however, the association was not statistically significant.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Obstructive sleep apnea syndrome (OSAS) and swallowing function—a systematic review

2020

View full text Add to dashboard Cite

Objectives The purpose of this systematic review was to summarize and qualitatively analyze published evidence elucidating the prevalence of dysphagia and detail alterations in swallowing function in patients with OSAS. Methods Computerized literature searches were performed from four search engines. The studies were selected based on the inclusion and exclusion criteria. The studies were screened using Covidence (Cochrane tool) and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement standards (PRISMA-2009). A total 2645 studies were initially retrieved, of which a total of 17 studies met inclusion criteria. Two reviewers, blinded to each other, evaluated level and strength of evidence using the Oxford Centre for Evidence-based Medicine Levels of Evidence and QualSyst, respectively. Results Dysphagia prevalence ranged from 16 to 78% among the eligible studies. Studies varied in operational definitions defining swallowing dysfunction (dysphagia) and method used to assess swallowing function. Approximately 70% of eligible studies demonstrated strong methodological quality. The majority of studies (n = 11; 65%) reported pharyngeal swallowing impairments in patients with OSAS, including delayed initiation of pharyngeal swallow and penetration/aspiration. Conclusion This systematic review describes swallowing function in patients with OSAS. However, due to the variability in defining OSAS and dysphagia, in the assessment method used to determine dysphagia, and heterogeneity of study designs, true prevalence is difficult to determine. Clinicians involved in the management of OSAS patients should employ validated assessment measures to determine if swallow dysfunction is present.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Obstructive sleep apnea syndrome (OSAS) and swallowing function—a systematic review

2020

View full text Add to dashboard Cite

show abstract

“…Undoubtedly, the results obtained reflect a broad characterization of the functions of the SS in obesity. Before bariatric surgery, patients with obesity suffer from respiratory disorders, such as alveolar hypoventilation and obstructive sleep apnea [ 63 ], apnea being a condition that has been reported on multiple occasions with a wide variety of evidence in scientific articles [ 13 , 18 , 20 , 44 , 57 , 60 , 82 ]. The respiratory mode of obese patients is oral because of the numerous structural changes; a chronic nasal obstruction is possibly maintained, thereby leading to attempts to restore the function that is vital for the patient’s survival and, consequently, affecting physiological breathing [ 18 , 36 ].…”

Section: Discussionmentioning

confidence: 99%

“…Changes in respiratory system compliance and lung volumes can negatively affect pulmonary gas exchange and lead to upper airway obstruction and sleep-disordered breathing. Therefore, the perioperative period should be carefully observed [ 82 ]. Among other things, decreased functional residual capacity, decreased expiratory reserve volume, decreased compliance, and increased resistance of the respiratory system imply breathing with low lung volume, promoting airway closure in dependent lung zones with consequent abnormalities in gas exchange, even though the capacity of the lungs to diffuse carbon monoxide is normal or increased [ 83 ].…”

Section: Discussionmentioning

confidence: 99%

Stomatognathic System Changes in Obese Patients Undergoing Bariatric Surgery: A Systematic Review

Gualdrón-Bobadilla

Briceño-Martínez

Caicedo-Téllez

et al. 2022

JPM

View full text Add to dashboard Cite

Background: Obesity is a multifactorial chronic disease involving multiple organs, devices, and systems involving important changes in the stomatognathic system, such as in the orofacial muscles, temporomandibular joint, cheeks, nose, jaw, maxilla, oral cavity, lips, teeth, tongue, hard/soft palate, larynx, and pharynx. Patients with obesity indicated for bariatric surgery reportedly presented with abnormalities in the structures and function of the stomatognathic apparatus. This occurs through the accumulation of adipose tissue in the oral cavity and pharyngeal and laryngeal regions. Therefore, this systematic review aimed to elucidate the changes occurring in the stomatognathic system of patients with obesity after undergoing bariatric surgery. Method: Information was searched based on the equations developed with the descriptors obtained in DECS and MESH using the PRISMA methodology. Studies published between 2010 and October 2021 in databases including PubMed, ProQuest, Scielo, Dialnet, EBSCO, and Springer Link were considered. Results: Eighty articles met the inclusion criteria after evaluating the articles, thereby allowing for the determination of the morphophysiological correlation of the stomatognathic system with the population studied. At the morphological or structural level, changes were observed in the face, nose, cheeks, maxilla, jaw, lips, oral cavity, teeth, tongue, palate, temporomandibular joint, neck, muscles, head, shoulders, larynx, and pharynx. At the morphological level, the main changes occurred in, and the most information was obtained from, the labial structures, teeth, muscles, pharynx, and larynx. Physiological changes were in breathing, phonation, chewing, and swallowing, thereby revealing the imbalance in basic and vital functions. Conclusions: Analyzing the changes and structures of obese patients and candidates for bariatric surgery revealed that, in the preoperative period, the evidence is clear owing to the presence of a wide range of information. However, the information is more limited regarding the postoperative period; thus, further research focusing on characterization of the system postoperatively is warranted.

show abstract

International Consensus Statement on Obstructive Sleep Apnea

Chang

Goldberg

Alt

et al. 2023

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Background: Evaluation and interpretation of the literature on obstructive sleep apnea (OSA) allows for consolidation and determination of the key factors important for clinical management of the adult OSA patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA). Methods: Using previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidencebased review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus. Results: The ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA treatment on multiple OSA-associated comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated. Conclusion:This review of the literature consolidates the available knowledge and identifies the limitations of the current evidence on OSA. This effort aims to create a resource for OSA evidence-based practice and identify future research needs. Knowledge gaps and research opportunities include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy.

show abstract

Laryngopharyngeal reflux and dysphagia in patients with obstructive sleep apnea: is there an association?

Cited by 14 publications

References 47 publications

Obstructive sleep apnea syndrome (OSAS) and swallowing function—a systematic review

Obstructive sleep apnea syndrome (OSAS) and swallowing function—a systematic review

Stomatognathic System Changes in Obese Patients Undergoing Bariatric Surgery: A Systematic Review

International Consensus Statement on Obstructive Sleep Apnea

Contact Info

Product

Resources

About