Laryngeal Papillomatosis in Adults: Assessment for Ten Years at the ENT Department of the National University Hospital of Fann (Dakar, Senegal)

Abstract

Objectives. The aim of this study was to describe the epidemiological, diagnostic, and therapeutic aspects of adult laryngeal papillomatosis in Senegal. Patients and Methods. This is a retrospective descriptive study of patients aged above 18 years with laryngeal papillomatosis and followed at the ENT department of the NUH of Fann between 01 January 2009 and 31 December 2018. Results. The mean age at diagnosis was 37.74 years and a sex ratio of 0.93. The 20–29 age group was the most represented (45.2%). The average consultation delay was 8.34 years. All patients had dysphonia at the moment of the diagnostic and in 35.5% of cases, and it was associated with laryngeal dyspnea. Glottis localization was present in all our patients, i.e., 100% of the cases. A tracheotomy was performed in 9.67% of cases. All of our patients have had their papilloma peeled per endoscopic with tweezers. No cases of malignant degeneration were found in our study. Conclusion. Laryngeal papillomatosis is the most common benign tumor of the larynx in both children and adults. Despite the progress of endoscopy and antiviral treatments, its treatment poses many problems in our undermedicalized countries.

Recurrent respiratory papillomatosis: clinical characteristics and viral genotyping in a Brazilian population

“…HPV-DNA was found in almost all laryngeal papillomatosis lesions, similar to the results observed by Sanchez 19 who reported a 95% prevalence of HPV-DNA in papillomatous lesions. The findings reported in other studies have also corroborated our results, confirming that HPV is the etiological agent of laryngeal papillomatosis 10,20,33 .…”

“…Matos et al 23 observed the presence of HPV-6 (72%) with respect to HPV-11 (28%) in 25 patients with laryngeal papillomatosis, in a Brazilian population. Eftekhaar et al 33 observed a prevalence of 75% of HPV-6 in relation to HPV-11 (16.7%) in 12 Iranian individuals. In a Swedish study of 55 patients, Hocevar et al 35 found that 76% of patients were infected with HPV-6 and 24% with HPV-11.…”