Laryngeal dystonia: case report and treatment with botulinum toxin

Santos, Victor José Barbosa; Mattioli, Fernando Marcos; Mattioli, Wellerson Marcos; Daniel, Renata Jacob; Cruz, Vicente Paulo Miranda

doi:10.1016/s1808-8694(15)30980-0

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Table 1 presents findings of BoNT treatments of LD and an overview of the literature on invasive brain modulation with deep brain stimulation (DBS) [ 77 , 78 , 79 , 80 , 81 ]. The efficacy and safety of BoNT were established for the treatment of LD, and this approach is considered by most to be the treatment of choice for spasmodic dysphonia/LD, particularly adLD [ 16 ].…”

Section: Focal Ld Treatment Optionsmentioning

confidence: 99%

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex

Vidaković

Gunjača

Bukic

et al. 2022

JCM

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Focal laryngeal dystonia (LD) is a rare, idiopathic disease affecting the laryngeal musculature with an unknown cause and clinically presented as adductor LD or rarely as abductor LD. The most effective treatment options include the injection of botulinum toxin (BoNT) into the affected laryngeal muscle. The aim of this narrative review is to summarize the patho-neuro-physiological and genetic background of LD, as well as the standard recommended therapy (BoNT) and pharmacological treatment options, and to discuss possible treatment perspectives using neuro-modulation techniques such as repetitive transcranial magnetic stimulation (rTMS) and vibrotactile stimulation. The review will present two LD cases, patients with adductor and abductor LD, standard diagnostic procedure, treatments and achievement, and the results of cortical excitability mapping the primary motor cortex for the representation of the laryngeal muscles in the assessment of corticospinal and corticobulbar excitability.

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Section: Focal Ld Treatment Optionsmentioning

confidence: 99%

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex

Vidaković

Gunjača

Bukic

et al. 2022

JCM

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Aplicação da técnica de emissão em tempo máximo de fonação em paciente com disfonia espasmódica adutora: relato de caso

Mota

Santos

Vasconcelos³

et al. 2012

Rev. soc. bras. fonoaudiol.

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Adductor Spasmodic Dysphonia (ASD) is a neurological disorder of central motor processing, characterized by involuntary and inappropriate contractions of the phonatory muscles, producing hyperadduction of the vocal folds, which causes a tremulous, faltering and strained-strangled voice. The aim of this study was to describe the vocal, acoustic and laryngeal parameters measured for a female patient with ADS pre and post speech therapy using the Technique of Sustained Maximum Phonation Time (SMPT). This technique aims to promote increase in glottal resistance, improve phonatory stability, and enhance glottal coaptation. A 66-year-old female patient with ASD took part in this study. She was submitted to otorhinolaryngologic and speech-language assessment before and after the application of the SMPT technique. The results showed modification of vocal, acoustic and laryngeal parameters, such as re-classifying her dysphonia from G 3 R 1 B 1 A 0 S 3 I 3 to G 2 R 1 B 1 A 0 S 2 I 2 , her pitch from severe to adequate, her spectrographic trace from unstable to more stable, and an expressive increase in mean fundamental frequency and mean vocal intensity, besides improvement of her glottal efficiency, with closure of the anteroposterior glottal opening. Speech therapy using the SMPT technique was considered a suitable treatment option for this case, given the good results obtained, especially the improvements in vocal quality and phonatory stability. The importance of further studies with the aim to provide greater scientific evidence for the effectiveness of the technique when treating ASD is emphasized.

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Laryngeal dystonia: case report and treatment with botulinum toxin

Cited by 2 publications

References 13 publications

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex

Aplicação da técnica de emissão em tempo máximo de fonação em paciente com disfonia espasmódica adutora: relato de caso

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