Laryngeal Desiccation Challenge and Nebulized Isotonic Saline in Healthy Male Singers and Nonsingers: Effects on Acoustic, Aerodynamic, and Self-Perceived Effort and Dryness Measures

The Effect of Hydration on Voice Quality in Adults: A Systematic Review

“…looked at the effect of oral desiccation and subsequent rehydration using nebulization of an isotonic saline solution [25]. Cepstral spectral index of dysphonia on the rainbow passage demonstrated significant negative effects by increasing after laryngeal desiccation (p=0.0047) [25]. The same results were not observed for sustained vowels (p=0.2399) [25].…”

“…Perceptual characteristics in CAPE-V scores (p=0.171) also revealed nonsignificance [44]. looked at the effect of oral desiccation and subsequent rehydration using nebulization of an isotonic saline solution [25]. Cepstral spectral index of dysphonia on the rainbow passage demonstrated significant negative effects by increasing after laryngeal desiccation (p=0.0047) [25].…”

“…Literature has emphasised the maintenance of adequate ingestion of liquids, the use of steam or both in combination as an important component of voice care and voice intervention Sivansankar & Fisher, 2003;Tanner, et al, 2015). However, the relationship between physiology, hydration and voicing is not yet fully understood.…”

“…Many studies have been conducted to determine the effect of hydration on the vocal folds and their functioning [9,[18][19][20][21][22] however, contradictory findings have been reported. The effects of dehydration can be seen on various aspects of voice acoustics; but the effects of rehydration or dehydration are contradictory, often indicating non-significant changes [9,19,20,[22][23][24][25][26].…”

A Method to Administer Agents to the Larynx in an Awake Large Animal

“…Nebulized isotonic saline is commonly used as a placebo in trials involving nebulized therapies and is also routinely used to promote mucus clearance of the airways (Eng et al, 1996;Goldman, Teale, & Muers, 1992;Jenkins, Heaton, Fulton, & Moxham, 1987;Sutton et al, 1988). Isotonic saline shows promise for voice problems associated with Sjogren's syndrome and inhaling dry air (Tanner et al, 2016;Tanner, Roy, Merrill, & Elstad, 2007). It is also the gold standard in testing new treatments and technologies.…”