Laryngeal Coccidioidomycosis

Ghosh, Jata S.

doi:10.1001/jama.1977.03280020033017

JAMA

1977

DOI: 10.1001/jama.1977.03280020033017

|View full text |Cite

Laryngeal Coccidioidomycosis

Jata S. Ghosh¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Published data on laryngeal coccidioidomycosis is sparse and limited to case reports or case series involving mainly adults and immunocompromised patients. [10][11][12][13][14][15][16][17][18][19][20] Recognizing children that may have laryngeal coccidioidomycosis is critical to ensure that appropriate evaluation and therapy is initiated.…”

mentioning

confidence: 99%

Pediatric Laryngeal Coccidioidomycosis: A Case Series in an Endemic Region

Naeem

McCarty

Rowe

et al. 2023

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

Background: Laryngeal coccidioidomycosis is a rare but life-threatening manifestation of coccidioidomycosis. Data in children are sparse and limited to case reports. We conducted this study to review the characteristics of laryngeal coccidioidomycosis in children. Methods: We performed a retrospective review of patients ≤21 years of age with laryngeal coccidioidomycosis who were treated from January 2010 to December 2017. We collected demographic data, clinical and laboratory studies and patient outcomes. Results: Five cases of pediatric laryngeal coccidioidomycosis were reviewed. All children were Hispanic and 3 were female. The median age was 1.8 years and the median duration of symptoms before diagnosis was 24 days. The most common symptoms included fever (100%), stridor (60%), cough (100%) and vocal changes (40%). Airway obstruction requiring tracheostomy and/or intubation for airway management was present in 80%. The most frequent location of lesions was the subglottic area. Coccidioidomycosis complement fixation titers were frequently low and culture/histopathology of laryngeal tissue was necessary to make a definitive diagnosis. All patients required surgical debridement and were treated with antifungal agents. None of the patients had recurrence during the follow-up period. Conclusions: This study suggests that laryngeal coccidioidomycosis in children presents with refractory stridor or dysphonia and severe airway obstruction. Favorable outcomes can be achieved with a comprehensive diagnostic work-up and aggressive surgical and medical management. With the rise in cases of coccidioidomycosis, physicians should have a heightened awareness regarding the possibility of laryngeal coccidioidomycosis when encountering children who have visited or reside in endemic areas with stridor or dysphonia.

show abstract

mentioning

confidence: 99%

Pediatric Laryngeal Coccidioidomycosis: A Case Series in an Endemic Region

Naeem

McCarty

Rowe

et al. 2023

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Laryngeal Coccidioidomycosis

Cited by 1 publication

References 0 publications

Pediatric Laryngeal Coccidioidomycosis: A Case Series in an Endemic Region

Pediatric Laryngeal Coccidioidomycosis: A Case Series in an Endemic Region

Contact Info

Product

Resources

About