Laryngeal chondrosarcoma: Two unusual cases

Bough, I. David; Chiles, Patrick J.; Fratalli, Mark A.; Vernose, Gerard

doi:10.1016/0196-0709(95)90045-4

Cited by 20 publications

(28 citation statements)

References 16 publications

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“…These symptoms are common to a variety of laryngeal pathologies, but what is striking is the duration of symptoms before tumor is diagnosed. In our series, the duration varied from a minimum of 3-4 months to 2 years, but symptoms up to 10 years and longer have been reported in the literature [5]. While dyspnea has been reported as the first presenting symptom in most series, hoarseness has been reported as the most common symptom by others [24,26].…”

Section: Discussionmentioning

confidence: 78%

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Long-term results of organ preservation in chondrosarcoma of the cricoid

Tiwari

Mahieu

Snow

1999

European Archives of Oto-Rhino-Laryngology

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Chondrosarcoma of the larynx is rare. The posterolateral lamina of the cricoid cartilage is the site most commonly involved. Although the symptomology, radiological and histopathological diagnostic features are well known, the condition continues to be diagnosed late and recurrences after excision are common. In general, radical surgical excision can result in long-term remission, although prognosis is related to the histopathological grade of the tumor. While a conservative surgical approach in low-grade tumors is justified, unexplained hoarseness, unilateral vocal cord paralysis and dyspnea requires CT scan examination.

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Section: Discussionmentioning

confidence: 78%

“…Its use in the larynx is presently indicated as an alternative when surgery is not possible or if the patient refuses surgery. CO 2 laser excision in patients with high operative risk has been advocated [5].…”

Section: Discussionmentioning

confidence: 99%

Long-term results of organ preservation in chondrosarcoma of the cricoid

Tiwari

Mahieu

Snow

1999

European Archives of Oto-Rhino-Laryngology

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“…The majority of these lesions arise from the posterior or posterolateral aspect of the cricoid. Other locations affected include the thyroid cartilage (17-18%), the arythenoids (5-8%), the corniculates (1%) and the epiglottis [2,8,9]. Occasionally more than one site is involved, as in the present case.…”

Section: Discussionmentioning

confidence: 54%

“…Grade I chondrosarcomas occur at any age [2]. With increasing age, grades II and III lesions occur more frequently, with a maximum in the fifth and sixth decades.…”

Section: Introductionmentioning

confidence: 99%

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Chondrosarcoma of the Larynx

Hof¹,

Kremer²,

Manni³

2000

Otorhinolaryngol Nova

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Chondrosarcoma of the larynx

Gripp

Pape

Schmitt

1998

Cancer

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on about 250 cases reported to date. The standard therapy is conservative surgery. Hildegard Pape, M.D.Radiotherapy has universally been regarded as ineffective in the treatment of this Gerd Schmitt, M.D.disease. METHODS.A patient with a laryngeal chondrosarcoma was observed for 11 years Department of Radiation Oncology, Heinrichafter radical radiotherapy. The literature on laryngeal chondrosarcoma was critiHeine-University Duesseldorf, Duesseldorf, Germany.cally reviewed, with emphasis placed on radiotherapy. RESULTS.The review of the literature revealed that experience with radiotherapy of laryngeal chondrosarcoma has been lacking, with fewer than 10 cases with short follow-up documented up to now. Meanwhile, increasing evidence of the efficacy of radiotherapy in the treatment of skeletal chondrosarcoma has emerged. The authors report the first case of chondrosarcoma of the larynx in which radical radiotherapy resulted in a long term remission of more than 10 years.CONCLUSIONS. Radiotherapy should be considered when radical surgery is not feasible without severe mutilation. It should also be considered for the treatment of residual disease. Laryngectomy should be restricted to salvage treatment when radiotherapy fails. In this study, radiotherapy appeared to be an effective modality in the treatment of low grade laryngeal chondrosarcoma, and these results contrast with the current widespread disapproval of this treatment. A mong neoplasms of the larynx, less than 1% are nonepithelial tumors, with chondrosarcoma being most common. 1 Approximately 250 laryngeal chondrosarcomas have been documented to date. Surgery is the mainstay of therapy, and limited experience with external radiation therapy (XRT) has been gained. 2,3 CASE REPORTA male patient age 66 years was admitted to the hospital with severe choking attacks that required emergency tracheotomy. The patient's history revealed episodes of progressive dyspnea over the last 3The authors thank Prof. James Kilbury for pamonths. Direct laryngoscopy showed a large, firm subglottic nodule tected with Feulgen staining corroborated the diagnosis of malignancy. A postoperative computed tomography (CT) scan (Fig.

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Laryngeal chondrosarcoma: Two unusual cases

Cited by 20 publications

References 16 publications

Long-term results of organ preservation in chondrosarcoma of the cricoid

Long-term results of organ preservation in chondrosarcoma of the cricoid

Chondrosarcoma of the Larynx

Chondrosarcoma of the larynx

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