Laryngeal Candidiasis Mimicking Malignancy

Abstract

Isolated laryngeal candidiasis in immunocompetent individuals is a rare entity with fewer than 40 cases reported in the literature. Laryngeal candidiasis secondary to inhaled steroid therapy is usually mild and has been reported in 10% to 15% of patients complaining of dysphonia during treatment. We present a case of laryngeal candidiasis mimicking laryngeal carcinoma in an immunocompetent patient being treated with inhaled fluticasone for chronic obstructive pulmonary disease. Biopsy of the lesion failed to show any signs of malignancy, and patient responded well to oral fluconazole therapy.

Laryngeal Candidiasis Mimicking Supraglottic Carcinoma by Prolonged Inhaled Steroid Therapy: A Case Report and Review of the Literature

“…Clinical presentation of fungal laryngeal dysfunction can vary. Main symptoms usually consist in sore throat, hoarseness, and dysphagia, 11,12 but respiratory distress, fever, cough, and/or Gerd-like symptoms are reported too. 7,13 Video-laryngoscopic pictures of fungal laryngitis in immune-competent host are not always typical and can be confusing.…”

A case report of invasive candidiasis and fungal osteomyelitis mimicking oropharyngeal carcinoma recurrence in an immunocompetent patient following transoral robotic surgery

“…Furthermore, given the patient’s recent diagnosis of oropharyngeal carcinoma, there was also a definite need to consider tumour recurrence despite initial biopsy showing granulation tissues with no neoplasia. There have been prior case reports of laryngeal candidiasis mimicking possible malignancy [19], [20], [21].…”

Klebsiella pneumoniae pharyngitis mimicking malignancy: a diagnostic dilemma

“…Other pharyngeal infections have been described that mimic malignancy including actinomycosis [6], syphilis [7], candidiasis [8], histoplasmosis [9], blastomycosis [10] and tuberculosis [11]. However, there are no reports of K. pneumoniae pharyngitis mimicking hypopharyngeal malignancy in the literature.…”