Laryngeal and Other Otolaryngologic Manifestations of Crohn's Disease

Nasal Septal Perforation in an Adolescent Girl with Crohn’s Disease: A Rare Extraintestinal Manifestation

“…Although an asymptomatic perforation rarely requires any treatment, topical nasal steroids, moisturizers, and antibacterial ointments are recommended in the literature for nasal CD [10]. When the extraintestinal lesions fail to respond to this therapy, systemic steroids become the mainstay of therapy [3,10,12]. Recently, infliximab (anti-TNF-α antibody) has shown a strong beneficial effect, especially in fistulous CD refractory to conventional therapy [13].…”

Obstructive sleep apnoea in a paediatric patient with laryngeal Crohn's disease

“…Laryngeal CD is uncommon, with only a few reported cases in the literature. Some anatomical sites of involvement reported so far include the arytenoids, aryepiglottic folds, epiglottis and other parts of the larynx. The majority of cases had gastrointestinal symptoms preceding laryngeal symptoms; however, they can appear even before gastrointestinal symptoms and may occur during a flare up of existing intestinal disease.…”

Asymmetric Mineralization of the Arytenoid Cartilages in Patients without Laryngeal Cancer

“…18 There are many reports of involvement of the larynx and more specifically the CAJ by various systemic diseases; however, there are no references in those reports to radiologic correlates of such involvement. These disorders include rheumatoid arthritis, 18 ankylosing spondylitis, 19 juvenile chronic arthritis, 20 autoimmune hepatitis, 21 pemphigus, 22 herpes zoster, 23 tuberculosis, 24 Wegener granulomatosis, 24 Crohn disease, 25 syphilis, 25 gout, 26 sarcoidosis, 27 and Sjogrens syndrome. 28 Most of the etiologies mentioned above usually manifest without a mass.…”