Laryngeal and laryngotracheal mucosa in reconstruction of the pharynx and proximal part of the esophagus

Lajtman, Z; Nosso, D.; Borčić, Vinko; Znaor, Tin

doi:10.1007/s002380050006

Cited by 2 publications

(1 citation statement)

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“…Subsequent reconstruction was performed by mobilization and rotation of`clear' laryngotracheal mucousus`¯ap' from the opposite side, our own reconstructive method. 12 If palpable or CT-evident metastatic spread to the lymph nodes was present, a neck dissection was performed in the patients undergoing surgery and radiotherapy. Ten patients in the chemotherapy and radiotherapy group had salvage surgery.…”

Section: Methodsmentioning

confidence: 99%

A comparison of surgery and radiotherapy in the management of advanced pyriform fossa carcinoma

Lajtman

Manestar

2001

Clin Otolaryngol

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This retrospective study analyses the outcome of treatment of 61 patients with advanced carcinoma of the pyriform fossa. Thirty-two patients (group 1) underwent surgery and postoperative radiotherapy and 29 patients (group 2) had induction chemotherapy followed by radiotherapy. The local recurrence-free survival at 5 years from the completion of therapy for group 1 was 54%, compared to 61% for group 2. The 5-year neck recurrence-free survival for groups 1 and 2 were 54% and 59%, respectively. The 5-year overall survival rates for groups 1 and 2 were 19% and 14%, respectively. Non-surgical therapy for advanced stage pyriform fossa cancer provides survival comparable with that achieved with the standard approach of surgery and postoperative radiotherapy. We advocate radical irradiation as the method of choice because it provides nodal coverage to the bilateral jugular chains and retropharyngeal nodes, all known to be at risk for metastases, and is associated with lower morbidity compared to surgery. But, however, despite the therapy, the outcome is poor.

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Section: Methodsmentioning

confidence: 99%