“…In the P. xylostella midgut transcriptome, 2,925 and 2,967 unigenes were differently expressed between two resistant strains compared to susceptible strains, respectively (Lei et al, ). The DEGs were primarily associated with Bt receptors (e.g., ABC transporter, APN, ALP, and CAD), digestive function (α‐amylase, lipase, protease, and carboxypeptidase), immune response (HSC70 and IL22), detoxication enzymes (P450, GST, and CarE), developmental genes (arylphorin), and a variety of binding proteins including cellular retinoic acid‐binding protein (lipid‐binding), insulin‐related peptide‐binding protein (protein‐binding), and ovary C/EBPg transcription factor (nucleic acid‐binding; Sparks, Blackburn, Kuhar, & Gundersen‐Rindal, ; Yang et al, ; Jurat‐Fuentes, Karumbaiah, & Jakka, ; Ocelotl et al, ; Shiho et al, ; Tristan, Sisi & John, , Yao et al, ; Castagnola et al, ; Chauhan et al, ). In this study, the common DEGs were also primarily associated with digestion function, with enriched GO terms including monocarboxylic acid metabolic process, pyruvate metabolic process, lipid biosynthetic process, and serine‐type endopeptidase activity.…”