Larva migrans in squirrel monkeys experimentally infected with Baylisascaris potosis

Tokiwa, Toshihiro; Tsugo, Kosuke; Nakamura, Shohei; Taira, Kensuke; Une, Yumi

doi:10.1016/j.parint.2015.03.003

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Exposure of gerbils to 100–4000 embryonated eggs resulted in VLM, but no larvae were found in the brain. A squirrel monkey ( Saimiri sciureus ) inoculated with 10,000 B. potosis eggs did not develop clinical signs or gross lesions, although a few migrating larvae were recovered from liver and kidney tissues (Tokiwa et al., 2015b). Another squirrel monkey inoculated with 100,000 eggs in the same trial developed gross lesions, including liver congestion, pulmonary edema, and abundant intestinal granulomas.…”

Section: New World Species Of Baylisascarismentioning

confidence: 99%

“…This animal was found dead at 30 DPI, but the animal lacked clinical signs and the authors state that no cause of death was determined. However, pulmonary edema, liver congestion, and nodular lesions containing non-degenerate larvae along the intestine were found at necropsy (Tokiwa et al., 2015b). Based on these preliminary trials, it appears that B. potosis can cause larva migrans in rodent and primate hosts, although the pathogenicity and capacity for neural invasion appears less than that of B. procyonis or B. columnaris.…”

Section: New World Species Of Baylisascarismentioning

confidence: 99%

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Beyond the raccoon roundworm: The natural history of non-raccoon Baylisascaris species in the New World

Sapp¹,

Gupta²,

Martin³

et al. 2017

International Journal for Parasitology: Parasites and Wildlife

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A total of 10 species of Baylisascaris, a genus of ascaridoid nematodes, occur worldwide and 6 of them occur in the New World. Most of the Baylisascaris species have a similar life cycle with carnivorous mammals or marsupials serving as definitive hosts and a smaller prey host serving as paratenic (or intermediate) hosts. However, one species in rodents is unique in that it only has one host. Considerable research has been conducted on B. procyonis, the raccoon roundworm, as it is a well-known cause of severe to fatal neurologic disease in humans and many wildlife species. However, other Baylisascaris species could cause larva migrans but research on them is limited in comparison. In addition to concerns related to the potential impacts of larva migrans on potential paratenic hosts, there are many questions about the geographic ranges, definitive and paratenic host diversity, and general ecology of these non-raccoon Baylisascaris species. Here, we provide a comprehensive review of the current knowledge of New World Baylisascaris species, including B. columnaris of skunks, B. transfuga and B. venezuelensis of bears, B. laevis of sciurids, B. devosi of gulonids, B. melis of badgers, and B. potosis of kinkajou. Discussed are what is known regarding the morphology, host range, geographic distribution, ecoepidemiology, infection dynamics in definitive and paratenic hosts, treatment, and control of these under-studied species. Also, we discuss the currently used molecular tools used to investigate this group of parasites. Because of morphologic similarities among larval stages of sympatric Baylisascaris species, these molecular tools should provide critical insight into these poorly-understood areas, especially paratenic and definitive host diversity and the possible risk these parasites pose to the health to the former group. This, paired with traditional experimental infections, morphological analysis, and field surveys will lead to a greater understanding of this interesting and important nematode genus.

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Section: New World Species Of Baylisascarismentioning

confidence: 99%

Section: New World Species Of Baylisascarismentioning

confidence: 99%

Beyond the raccoon roundworm: The natural history of non-raccoon Baylisascaris species in the New World

Sapp¹,

Gupta²,

Martin³

et al. 2017

International Journal for Parasitology: Parasites and Wildlife

View full text Add to dashboard Cite

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Prevalence ofBaylisascarisRoundworm in Captive Kinkajous in Japan

Tokiwa

Sugiyama

Taira

et al. 2016

Journal of Parasitology

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Baylisascaris potosis causes larva migrans in animals. The present study evaluated the prevalence of B. potosis in captive kinkajous ( Potos flavus ) and the ability of milbemycin to treat natural infections of B. potosis in 2 female wild-caught kinkajous. In 2012, fecal samples were collected from 16 kinkajous in 6 zoological gardens and 29 imported captive kinkajous from 4 pet traders in Japan. Although all samples from zoological gardens were negative, 8 kinkajous from traders were positive for Baylisascaris eggs, at least 4 of which were wild caught in the Republic of Guyana. No associated human illness was reported from any of the facilities. The 2 infected kinkajous received a single oral administration of Milbemycin® A Tablets, which delivers 0.69-0.89 mg/kg milbemycin oxime. Fecal examinations on days 14 and 30 were negative for Baylisascaris eggs. These results demonstrated that milbemycin oxime has possible anthelmintic efficacy against Baylisascaris roundworms in captive kinkajous. We conclude that Baylisascaris infections are highly prevalent in wild-caught kinkajous in Japan and that most of the infected kinkajous were imported from the Republic of Guyana.

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Larva migrans in squirrel monkeys experimentally infected with Baylisascaris potosis

Cited by 2 publications

References 14 publications

Beyond the raccoon roundworm: The natural history of non-raccoon Baylisascaris species in the New World

Beyond the raccoon roundworm: The natural history of non-raccoon Baylisascaris species in the New World

Prevalence ofBaylisascarisRoundworm in Captive Kinkajous in Japan

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