Largest Phyllodes Tumor- Case Report and Brief Review Article

Kumar, Tarun; Patel, Mahesh D.; Bhargavan, Rexeena; Kumar, Prabhat; Patel, Madhabhai M.; Kothari, Kiran; Brahmbhatt, Bina

doi:10.1007/s13193-011-0077-3

Cited by 17 publications

(14 citation statements)

References 12 publications

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“…Radiotherapy may have a role in the treatment of PT depending on the number of recurrences, mitotic index, bulky tumor, status of resection margins, and p53 and Ki67 expression. 20 Adjuvant radiation therapy has been recommended for malignant PTs in the belief that this should be managed as a soft tissue sarcoma with resection and to reduce the risk of local recurrence. Some authors recommend radiation therapy for patients with positive surgical margins, tumor size >5 cm, and for patients who received lumpectomy for primary treatment.…”

Section: Discussionmentioning

confidence: 99%

Malignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review

Pacioles

Seth

Orellana

et al. 2014

CMAR

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Phyllodes tumors are rare fibroepithelial neoplasms that account for less than 1% of all breast tumors and are typically found in middle-aged women. Phyllodes tumors that present with hypoglycemia are even rarer. No one morphologic finding is reliable in predicting the clinical behavior of this tumor. Surgery has been the primary mode of treatment to date. However, the extent of resection and the role of adjuvant radiotherapy or chemotherapy are still controversial. Here, we present a challenging case of malignant phyllodes tumor of the breast associated with hypoglycemia, and review the literature regarding clinical findings, pathologic risk factors for recurrence, and treatment recommendations.

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Section: Discussionmentioning

confidence: 99%

Malignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review

Pacioles

Seth

Orellana

et al. 2014

CMAR

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“…Phyllodes tumor is the currently accepted nomenclature according to the World Health Organization.' 5 Phyllodes tumors are fibroepithelial tumors of the breast, representing 2-3% of all fibroepithelial tumors, and <1% of all breast tumors. 6 Phyllodes tumors are uniquely found in breast tissue and histologically have both an epithelial component as well as metaplastic mesenchymal (stromal) component.…”

Section: Discussionmentioning

confidence: 99%

Recurrent phyllodes tumor of the breast transforming to a fibrosarcoma

et al. 2014

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Phyllodes tumors are fibroepithelial tumors of the breast, representing 2-3% of all fibroepithelial tumors, and <1% of all breast tumors. Malignant transformation may occur usually within stromal component of phyllodes tumor. Careful characterization of the stromal compartment is critical, since it is the pathologic features of stromal cells that determine its malignant potential. Primary sarcomas of the breast are extremely rare and account for <0.1% of all malignant tumor of the breast, of which the conversion of a phyllodes tumor to sarcoma of the breast is even very rare and only two cases have ever been reported. We present a case of recurrent phyllodes tumor of the breast transforming to a fibrosarcoma.

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“…Malignant tumors usually have rhabdomyosarcoma and liposarcoma rather than fibrosarcomas, the number of mitoses is of great help in the diagnosing the malignant subtype [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Phyllodes tumor in pregnancy: A Case Report

Patil

Rajpal²,

Pandya

et al. 2019

Obs Gyne Reivew J Obstet Gynecol

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Phyllodes tumor accounts for less than 1% of all breast neoplasms. These tumors are fast growing masses arising from the periductal stromal cells of the breast. We report a case of phyllodes in a 25 year old primigravida who presented to us at 18 weeks of pregnancy with mass of right breast which appeared 15 days back. She gave history of some mass in right breast for which she was operated 1 year back for which no details or papers were available. On examination there was a tumor in Right breast of about 20x15x11 cm size.ANC examination showed uterus of 18 wks size, FHS 140/min, regular. Patient underwent FNAC and biopsy from the mass which was suggestive of malignant Phyllodes tumor. Patient was prepared for mastectomy and along with surgical team right mastectomy with right axillary lymph node dissection was done. Post-operative period was uneventful. Histopathological examination showed increased cellularity and nuclear atypia suggestive of malignant phyllodes tumour and lymph nodes were negative. We concluded that accurate preoperative pathological diagnosis is very important for management of phyllodes tumor, and allows correct surgical planning and avoidance of reoperation.

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Largest Phyllodes Tumor- Case Report and Brief Review Article

Cited by 17 publications

References 12 publications

Malignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review

Malignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review

Recurrent phyllodes tumor of the breast transforming to a fibrosarcoma

Phyllodes tumor in pregnancy: A Case Report

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