Large vessel vasculitis: is it more common than usually assumed?

Cimmino, Marco A.; Camellino, Dario

doi:10.4081/reumatismo.2017.1033

Cited by 5 publications

(4 citation statements)

References 15 publications

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“…In conclusion, our findings indicate that in patients with classic PMR, besides pelvic girdle pain, the presence of inflammatory low back pain and diffuse lower limb pain may have clinical relevance to identify a LVV by 18 F-FDG PET/CT scan. In agreement with experts in the field [28], we feel that higher physician awareness and broader use of vascular imaging techniques to disclose LVV involvement is needed in patients with PMR.…”

Section: Discussionsupporting

confidence: 73%

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Predictors of positive 18F-FDG PET/CT-scan for large vessel vasculitis in patients with persistent polymyalgia rheumatica

Prieto-Peña

Martínez-Rodríguez

Loricera

et al. 2019

Seminars in Arthritis and Rheumatism

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Section: Discussionsupporting

confidence: 73%

“…Early detection of LVV in patients with PMR is of potential relevance to determine the actual spectrum of the disease [26][27][28]. 18 F-FDG PET/CT has demonstrated to be very sensitive to make an early diagnosis of LVV [29][30][31][32][33][34][35][36].…”

Section: Discussionmentioning

confidence: 99%

Predictors of positive 18F-FDG PET/CT-scan for large vessel vasculitis in patients with persistent polymyalgia rheumatica

Prieto-Peña

Martínez-Rodríguez

Loricera

et al. 2019

Seminars in Arthritis and Rheumatism

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“…Conversely, it remains unclear how PMR patients with subclinical LVV (found incidentally by imaging during work-up) should be treated. With the advent of new imaging techniques, such as positron emission tomography (PET) and angiography with magnetic resonance imaging (MRA), the vascular tracer accumulation has been demonstrated in about one-third of patients with apparently isolated PMR (50,51). Previous studies suggested that PMR patients without clinical signs of GCA but with a positive temporal artery biopsy are not at a higher risk of vasculitic complications such as visual loss (27,52).…”

Section: Biologic Dmardsmentioning

confidence: 99%

Update on treatment of polymyalgia rheumatica

Camellino

Dejaco²

2018

Reumatismo

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SUMMARYPolymyalgia rheumatica (PMR) is the second most common inflammatory rheumatic disease in the elderly after rheumatoid arthritis. It is clinically characterised by pain and stiffness in the neck, proximal shoulder and hip girdle. Glucocorticoids (GCs) are the cornerstone of PMR treatment, but they are associated with potentially severe side effects. Among GC-sparing agents, methotrexate revealed a modest benefit in clinical trials, and recently, there have been promising reports from tocilizumab. In this review, we summarize the available evidence on the treatment of PMR and the possible role in the future of other agents under investigation.

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“…n INTRODUCTION G iant cell arteritis (GCA) is a large vessel vasculitis affecting elderly people, with the highest incidence among persons aged between 70 and 79 years (1). The frequency of this condition is probably higher than commonly believed (2) and is expected to increase, because of the increasing age of the general population. It has been estimated that between 2014 and 2050, more than 3 million people will have been diagnosed with GCA in Europe, North America and Oceania (3).…”

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confidence: 99%

Management of giant cell arteritis among general practitioners from Genoa, Italy: a web-based survey

et al. 2021

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Giant cell arteritis (GCA) is the most common form of vasculitis of the adult. General practitioners (GPs) are usually the first physicians who take care of GCA patients. In this study, the awareness of GPs from Genoa, Italy, regarding GCA was investigated by a web-based survey. A web-based questionnaire was sent by mail to 775 Italian GPs. It included 12 multiple choice questions regarding practice seniority, practice population size, number of GCA patients followed, and GPs’ diagnostic and therapeutic approach. Of the 775 GPs involved, 76 (9.8%) answered. Thirty-three/75 (44%) declared that they did not see patients with GCA and the remaining 42 (56%) that they diagnose between one and two patients per year. New headache onset was the presenting feature of GCA for the majority of GPs (78.3%). GCA was diagnosed on the basis of clinical presentation alone by 35.2% of them, of temporal artery biopsy by 49.3%, and by imaging, including ultrasound and magnetic resonance imaging, by 15.5%. The referral pattern was mainly toward rheumatologists (68.5%). Only 27.8% GPs declared they start treatment at the first clinical suspicion, with the others waiting for laboratory and imaging examinations or specialist consultation. The doses of glucocorticoids used were in keeping with current guidelines. The management of GCA by GPs from Genoa is in general correct, with the exceptions of excessive confidence in headaches for diagnosis and of the timing of GC initiation. These points suggest that a program of information and education for GPs is warranted.

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Large vessel vasculitis: is it more common than usually assumed?

Abstract: Not available

Cited by 5 publications

References 15 publications

Predictors of positive 18F-FDG PET/CT-scan for large vessel vasculitis in patients with persistent polymyalgia rheumatica

Predictors of positive 18F-FDG PET/CT-scan for large vessel vasculitis in patients with persistent polymyalgia rheumatica

Update on treatment of polymyalgia rheumatica

Management of giant cell arteritis among general practitioners from Genoa, Italy: a web-based survey

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