Large schwannoma of the sciatic nerve

A rare cause of sciatica: Sciatic nerve schwannoma

“…The final diagnosis is possible by histological analysis [9]. Enzinger and Weis described the several microscopic feature characteristic of a schwannoma, found in our case.…”

“…MRI identified the tumor and its contacts with the nerve. It showed a wellcircumscribed and eccentrally mass located on the nerve [2,9,10].…”

“…In the lower limbs, Schwannoma is often located in the posterior tibial nerve [6,7]. A sciatic localization is rare, observed in 1% of the patients [1,4,[8][9][10].…”

Extra-spinal sciatica and sciatica mimics: a scoping review

“…A schwannoma is the most common benign peripheral nerve sheath tumor of the SN. It represents 8% of all soft tissue tumors involving the SN [ 78 ]. In case of sciatica-like pain with negative lumbar MRI scanning for disc herniation, potential SN schwannoma along its pelvic and extra-pelvic courses (near the ischial tuberosity, gluteal region, posterior to the hip joint, and lower thigh) should be investigated [ 78 - 80 ].…”

“…It represents 8% of all soft tissue tumors involving the SN [ 78 ]. In case of sciatica-like pain with negative lumbar MRI scanning for disc herniation, potential SN schwannoma along its pelvic and extra-pelvic courses (near the ischial tuberosity, gluteal region, posterior to the hip joint, and lower thigh) should be investigated [ 78 - 80 ]. Simultaneous presence of neurofibroma and schwannoma compressing the the SN with sciatica-like features, unveiled under MRI/MSUS scanning, has also been reported; surgical excision improves symptoms [ 79 , 81 ].…”