Large-scale assessment of organic contaminant emissions from chemical and pharmaceutical manufacturing into Swiss surface waters

Anliker, Sabine; Santiago, Sérgio Lima; Fenner, Kathrin; Singer, Heinz

doi:10.1016/j.watres.2022.118221

Cited by 14 publications

(7 citation statements)

References 23 publications

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“…The concentrations of tetracycline and oxytetracycline in soil were higher, which may be caused by the strong transformation ability of macrolides (adsorbed by soil or reacted with microorganisms in soil) 8 . PPCPs in the WWTP sample reached the μg/L level, confirming that WWTPs have a great impact on the discharge of ECs 51 . Nonylphenol was not found in either river or soil samples, but it was detected in the WWTP sample with a concentration of 4 μg/l.…”

Section: Resultsmentioning

confidence: 80%

“…8 PPCPs in the WWTP sample reached the μg/L level, confirming that WWTPs have a great impact on the discharge of ECs. 51 Nonylphenol was not found in either river or soil samples, but it was detected in the WWTP sample with a concentration of 4 μg/l. This method overcomes the difficulty of balancing a low detection limit and simultaneous detection.…”

Section: Application To Environmental Samplesmentioning

confidence: 91%

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An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

Yao

et al. 2022

Rapid Comm Mass Spectrometry

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Rationale The development of appropriate analytical screening techniques for pharmaceuticals and personal care products (PPCPs) is the basis for studying the distribution and environmental impact of emerging contaminants (ECs). Mass spectrometry‐based screening methods vary with the complexity of the target compounds. It is challenging to balance both positive and negative ion quantification with a low detection limit. To establish a set of experimental methods including extraction, chromatography‐separation and mass spectrometry screening is one of the most important topics in PPCP research. This paper describes a universal and efficient qualification and quantification protocol for the simultaneous detection of 34 PPCPs in different environmental samples in a single analytical data acquisition run. Methods Thirty‐four representative PPCPs, which are widely distributed in the environment with high ecological toxicity and complex chemical structures, were selected as representative target ECs. The extraction of the target PPCPs was achieved using only one solid‐phase extraction cartridge without the need to adjust the pH of samples. The enriched samples were detected by LC–MS/MS in both positive and negative ion modes simultaneously. The protocol was evaluated based on the accuracy, precision, detection limits and matrix effects. Results This method achieved simultaneous detection of PPCPs in both positive and negative ion modes, with a single analytical cycle of 12 min. The observed SPE recoveries were between 40% and 115%. The instrumental detection limits (IDL) varied from 0.01 to 1 pg, and the method detection limits (MDL) were between 0.002 and 3.323 ng/l in different matrices. Most of the PPCPs were subjected to matrix suppression below 30%. The method was successfully applied for quantitative analysis of the PPCPs in different environmental samples, including river samples, wastewater treatment plant (WWTP) samples and soil samples. Conclusions This protocol developed a rapid and efficient detection method to simultaneous qualitative and quantitative 34 representative PPCPs in the environment. The IDL ranged from 0.01 to 1 pg and the MDL ranged from 0.002 to 3.323 ng/l in different matrices. The detection limit was one order of magnitude lower compared to previous studies. The protocol also provided a wide application range for different environmental matrices, which permitted the migration and transformation of PPCPs to be explored.

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Section: Resultsmentioning

confidence: 80%

Section: Application To Environmental Samplesmentioning

confidence: 91%

An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

Yao

et al. 2022

Rapid Comm Mass Spectrometry

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“…Typically regulated through industrial pretreatment programs, an enhanced sewer source (or “sewershed”) protection entreats industries to pretreat their wastewater before discharging into the sewer. , Although past applications of sewershed protection have focused on protecting drinking water quality from reuse, enhanced sewershed protection has the expanded goal of reducing the cost of MWRC management. Furthermore, the stewardship of recalcitrant micropollutants should also extend beyond the parent compound to transformation products that are likely to arise in wastewater treatment and the natural environment. − …”

Section: Enabling Reuse Through Mwrc Regulationsmentioning

confidence: 99%

The Future of Municipal Wastewater Reuse Concentrate Management: Drivers, Challenges, and Opportunities

Finnerty,

Childress,

Hardy

et al. 2023

Environ. Sci. Technol.

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Water reuse is rapidly becoming an integral feature of resilient water systems, where municipal wastewater undergoes advanced treatment, typically involving a sequence of ultrafiltration (UF), reverse osmosis (RO), and an advanced oxidation process (AOP). When RO is used, a concentrated waste stream is produced that is elevated in not only total dissolved solids but also metals, nutrients, and micropollutants that have passed through conventional wastewater treatment. Management of this RO concentrate�dubbed municipal wastewater reuse concentrate (MWRC)�will be critical to address, especially as water reuse practices become more widespread. Building on existing brine management practices, this review explores MWRC management options by identifying infrastructural needs and opportunities for multi-beneficial disposal. To safeguard environmental systems from the potential hazards of MWRC, disposal, monitoring, and regulatory techniques are discussed to promote the safety and affordability of implementing MWRC management. Furthermore, opportunities for resource recovery and valorization are differentiated, while economic techniques to revamp cost-benefit analysis for MWRC management are examined. The goal of this critical review is to create a common foundation for researchers, practitioners, and regulators by providing an interdisciplinary set of tools and frameworks to address the impending challenges and emerging opportunities of MWRC management.

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“…With the development of synthetic chemistry, a large amount of waste is produced, especially in the large‐scale manufacturing process of chemicals, which brings a serious burden on the environment. [ 1 ] In this context, the recycling of in situ generated waste as reagents and turning them into chemicals is a state‐of‐the‐art protocol in sustainable green chemistry. Up to now, only a handful of innovative works have laid a stepping stone to advance the circular economy of synthetic chemistry.…”

Section: Introductionmentioning

confidence: 99%

Aminohalogenation of maleimides with alkylamines and XCH₂CH₂X (X = Cl, Br)

Wang

Chen

et al. 2023

Applied Organom Chemis

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The nucleophilic substitution of organohalides with alkylamines is one of the most heralded reactions in synthetic chemistry. However, the resulting halide anions are often wasted in routine workup experiments and not fully utilized. Herein, we report a halogen recycling strategy for radical aminohalogenation of maleimides with XCH2CH2X (X = Cl, Br) and alkylamines with excellent functional group compatibility. The strategy's excellent generality is demonstrated by 38 aminohalogenated products, twofold aminochlorination, and late‐stage vinylchlorination of nortriptyline.

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Large-scale assessment of organic contaminant emissions from chemical and pharmaceutical manufacturing into Swiss surface waters

Cited by 14 publications

References 23 publications

An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

The Future of Municipal Wastewater Reuse Concentrate Management: Drivers, Challenges, and Opportunities

Aminohalogenation of maleimides with alkylamines and XCH₂CH₂X (X = Cl, Br)

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Large-scale assessment of organic contaminant emissions from chemical and pharmaceutical manufacturing into Swiss surface waters

Cited by 14 publications

References 23 publications

An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

An advanced LC–MS/MS protocol for simultaneous detection of pharmaceuticals and personal care products in the environment

The Future of Municipal Wastewater Reuse Concentrate Management: Drivers, Challenges, and Opportunities

Aminohalogenation of maleimides with alkylamines and XCH2CH2X (X = Cl, Br)

Contact Info

Product

Resources

About

Aminohalogenation of maleimides with alkylamines and XCH₂CH₂X (X = Cl, Br)