Large renal leiomyoma: A multidisciplinary approach to diagnosis

Chaniotakis, Sotiris; Yang, Yi; Patel, Tulsi; Banks, James

doi:10.3941/jrcr.v15i8.4125

Cited by 3 publications

(2 citation statements)

References 26 publications

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“…Cells are long fusiform spindled, with abundant eosinophilic cytoplasm and bland, elongated nucleus with blunt ends (so called cigar-or box-car-shaped). The tumor shows absence of mitotic figures, pleomorphism, hyperchromatism, or perilesional invasivity (3,4,5). Stroma is variably collagenized.…”

Section: Discussionmentioning

confidence: 99%

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Leiomyoma of Kidney

Bhaskarashenoy,

Sukumaran

2023

jkcvhl

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Renal leiomyomas are rare benign mesenchymal tumors of kidney that affect adults of second to sixth decade. They can present as small asymptomatic multifocal lesions that are identified only in autopsy, or as large solitary lesions that cause pain and abdominal distention. Histomorphologically it appears exactly like its counterpart in other soft tissues. Differentiating renal leiomyoma from the lipid-poor angiomyolipoma is difficult by morphology, hence immunohistochemical studies are recommended. The case described is that of a female patient aged 74 years with a small solitary lesion in right kidney, who presented with history of pain and abdominal distention. She underwent wedge resection, histopathologically and immunohistochemically diagnosed as renal leiomyoma.

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Section: Discussionmentioning

confidence: 99%

“…Neither the positivity with SMA and desmin nor the negativity with S100 can differentiate between angiomyolipoma and leiomyoma. HMB45-negative lipid-poor angiomyolipomas have shown c-Kit positivity (4,5).…”

Section: Discussionmentioning

confidence: 99%

Leiomyoma of Kidney

Bhaskarashenoy,

Sukumaran

2023

jkcvhl

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Huge Renal Leiomyoma Masqurading as Cystic Renal Cell Carcinoma: a case report

Idowu,

Adekunle,

Rasheed

et al. 2023

Afr J Urol

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Background Renal leiomyoma is an extremely rare benign tumour of the kidney. It is mostly asymptomatic. Our aim was to report the first case of symptomatic renal leiomyoma in Nigeria which was suspected to be renal cell carcinoma and our objective was to document the clinical, radiological, histological and treatment of this rare lesion. Case presentation We describe a 46-year-old woman with a two-week history of right flank pain and intermittent haematuria. The examination was remarkable for the ballotable right kidney. Abdominopelvic sonogram and computed tomography were suggestive of cystic right renal mass with suspicion of right renal cell carcinoma. She had surgical resection of the mass and histopathological analysis showed renal leiomyoma. Conclusion We have illustrated our experience on the first case of symptomatic renal leiomyoma masquerading as cystic renal cell carcinoma in Nigeria. A high index of suspicion is required for accurate diagnosis. This may go a long way in considering kidney-sparing surgery rather than radical nephrectomy.

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Renal leiomyoma - case report and literature review

Grbic,

Filipovic,

Vojinov

et al. 2023

Med pregl

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Introduction. Leiomyoma is a mesenchymal benign tumor that seldom manifests in the kidney. Typically, these tumors are small, asymptomatic, and often detected accidentally. Differentiating leiomyomas radiologically from other renal neoplasms, particularly renal cell carcinomas, poses a considerable challenge before surgical intervention. Moreover, the conclusive diagnosis of leiomyomas can only be established through histopathological and immunohistochemical evaluation following surgical intervention. Case Report. We present a case of a 44-year-old woman who was diagnosed with right kidney leiomyoma accidentally during a computed tomography examination following exploratory curettage by a gynecologist. An enhanced computed tomography scan revealed a 10 mm tumor located on the upper pole of the right kidney, extending beyond its boundaries. The imaging differential diagnosis was renal cell carcinoma of the right kidney. A laparoscopic partial nephrectomy was performed. Macroscopically, the tumor appeared subcapsular, well-defined, with a firm consistency and a tan-white whorled cut surface. The histological characteristics and the supporting immunohistochemical profile confirmed the diagnosis of renal leiomyoma. The postoperative course was uneventful, and the patient was discharged on the 3rd postoperative day. Conclusion. Leiomyomas are rare kidney tumors. A conclusive diagnosis is established through histopathological findings. The pre-operative differentiation of leiomyomas radiologically from other renal neoplasms, particularly renal cell carcinomas, poses a considerable challenge in radiological assessment.

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Large renal leiomyoma: A multidisciplinary approach to diagnosis

Cited by 3 publications

References 26 publications

Leiomyoma of Kidney

Leiomyoma of Kidney

Huge Renal Leiomyoma Masqurading as Cystic Renal Cell Carcinoma: a case report

Renal leiomyoma - case report and literature review

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