Large Pelvic Masses of Obscure Origin: Urologist’s Perspective

Kumar, Santosh; Sarkar, Debansu; Prasad, Seema; Gupta, Vikash; Ghosala, Prithwiraj; Kaman, Lileshwar; Yadav, Thakur Deen; Ganesamoni, Raguram; Singh, Shrawan Kumar

doi:10.1159/000334332

Cited by 10 publications

(3 citation statements)

References 50 publications

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“…Besides the classical treatment in breast cancer its antifibroblastic effect is also used in the treatment of Peyronie's disease and pelvic fibromatosis [22,23,24]. …”

Section: Discussionmentioning

confidence: 99%

Tamoxifen Monotherapy in the Treatment of Retroperitoneal Fibrosis

Brandt¹,

Kamper

Kukuk³

et al. 2014

Urol Int

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Objective: To evaluate the therapeutic effect of tamoxifen monotherapy in patients with retroperitoneal fibrosis (RPF). Patients and Methods: From 2007 on, 31 patients with idiopathic RPF were treated with tamoxifen monotherapy. Follow-up investigations included magnetic resonance imaging, laboratory measurements, registration of side effects and changes or removal of ureteral stents. Data were stored in the Else Kröner-Fresenius Registry of Retroperitoneal Fibrosis. Results: 25 men and 6 women with a mean age of 56.6 years were treated with tamoxifen monotherapy. Mean duration of treatment was 13.3 months, mean follow-up 26.8 months. A total of 44 renal units were affected by hydronephrosis and covered by DJ stents. Radiological regression of fibrosis was detected in 22 cases (71.0%); removal of ureteral stents was possible in 27/44 renal units (61.4%) and 17/29 patients (58.6%), respectively. Most patients showed only mild or no side effects of therapy. In 7 cases (22.3%) tamoxifen therapy had to be abandoned because of severe side effects, progression of fibrosis or persistent intolerance. Conclusions: Tamoxifen is an alternative in the medical treatment of RPF, especially if patients want to avoid glucocorticoids. The potential of regression of fibrosis seems to be slightly inferior and the relapse rate is higher compared to steroids, but the rate of successful DJ removals is comparable.

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“…Besides the classical treatment in breast cancer its antifibroblastic effect is also used in the treatment of Peyronie's disease and pelvic fibromatosis [22,23,24]. …”

Section: Discussionmentioning

confidence: 99%

Tamoxifen Monotherapy in the Treatment of Retroperitoneal Fibrosis

Brandt¹,

Kamper

Kukuk³

et al. 2014

Urol Int

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“…However, the pelvic anatomy is complex and poses great challenges to orthopedic surgeons, as sarcomas are often large in size. They are typically enclosed in the narrow confines of the pelvis with the close proximity of vital structures such as iliac vessels, ureters, urinary bladder and rectum [2,[6][7][8][9]. Advances in perioperative radiological assessment and in surgical techniques make the aggressive management of primary pelvic sarcoma possible.…”

Section: Introductionmentioning

confidence: 99%

“…Preoperative magnetic resonance imaging (MRI) allows for more accurate operative planning, thus allowing surgeons to perform more complex resections, with bone, muscular and neurovascular dissection and resection [10]. Nonetheless, the proximity of all pelvic organs makes them susceptible to injury during pelvic surgery [6,11]. Iatrogenic injuries are currently the most common cause of visceral trauma [12].…”

Section: Introductionmentioning

confidence: 99%

A Planned Multidisciplinary Surgical Approach to Treat Primary Pelvic Malignancies

et al. 2023

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The pelvic anatomy poses great challenges to orthopedic surgeons. Sarcomas are often large in size and typically enclosed in the narrow confines of the pelvis with the close proximity of vital structures. The aim of this study is to report a systematic planned multidisciplinary surgical approach to treat pelvic sarcomas. Seventeen patients affected by bone and soft tissue sarcomas of the pelvis, treated using a planned multidisciplinary surgical approach, combining the expertise of orthopedic oncology and other surgeons (colleagues from urology, vascular surgery, abdominal surgery, gynecology and plastic surgery), were included. Seven patients were treated with hindquarter amputation; 10 patients underwent excision of the tumor. Reconstruction of bone defects was conducted in six patients with a custom-made 3D-printed pelvic prosthesis. Thirteen patients experienced at least one complication. Well-organized multidisciplinary collaborations between each subspecialty are the cornerstone for the management of patients affected by pelvic sarcomas, which should be conducted in specialized centers. A multidisciplinary surgical approach is of paramount importance in order to obtain the best successful surgical results and adequate margins for achieving acceptable outcomes.

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Ovarian mucinous cystadenoma causing acute urinary retention

Pulvino

Resnick

Wax

2021

J of Clinical Ultrasound

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Acute urinary retention rarely occurs in women, and is only infrequently caused by a pelvic mass. We describe a case of acute urinary retention caused by a large ovarian mucinous cystadenoma. Point of care ultrasound characterized and localized the lesion, while computerized tomography demonstrated the anatomic distortions resulting in urinary retention. The patient's symptoms resolved immediately following a laparoscopic right salpingo‐oophorectomy with complete tumor removal.

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Large Pelvic Masses of Obscure Origin: Urologist’s Perspective

Cited by 10 publications

References 50 publications

Tamoxifen Monotherapy in the Treatment of Retroperitoneal Fibrosis

Tamoxifen Monotherapy in the Treatment of Retroperitoneal Fibrosis

A Planned Multidisciplinary Surgical Approach to Treat Primary Pelvic Malignancies

Ovarian mucinous cystadenoma causing acute urinary retention

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