Large hemorrhage due to venipuncture in the elbow of a patient with severe hemophilia: A case report and literature review

Lyu, Jingtong; Wu, Wenjie; Xiang, Zhou; Huang, Fuguo

doi:10.3892/etm.2016.2990

Cited by 1 publication

(1 citation statement)

References 14 publications

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“…ACS is a rare but potentially devastating complication after venipuncture in people with hemophilia. 18 Uncontrolled hemorrhage may generate a critical intersti-tial pressure in the closed osseo-fascial compartment. The elevation of pressure causes microvascular compromise and a reduction in the perfusion gradient.…”

Section: Discussionmentioning

confidence: 99%

The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome

et al. 2021

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Hemophilias are hemorrhagic congenital rare diseases. The gold standard of therapy in hemophilics is the intravenously replacement therapy. We can infuse intravenously plasma derived factors (FVIII for Hemophilia A and FIX for Hemophilia B) or recombinant products (i.e. clotting factor synthetically produced). Venipuncture is not a safe procedure in subjects with hemorrhagic diseases. It is considered an invasive technique with potential massive bleeding and it requires standardized procedures to prevent complications. Local pressure after the procedure (with eventually ice rest) must be always done. In case of bleeding a rapid replacement therapy must be conducted. A severe complication in hemophilia is compartment syndrome. We report a case of massive bleeding in a hemophilic newborn after venipuncture and a literature review of compartment syndrome in hemophiliacs. The aim of this paper is to help physicians in the clinical management to prevent the evolution of a massive bleeding in compartment syndrome.

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Section: Discussionmentioning

confidence: 99%

The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome

et al. 2021

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Large hemorrhage due to venipuncture in the elbow of a patient with severe hemophilia: A case report and literature review

Abstract: Abstract. Hemophilia A, which is the most common form of hemophilia, is caused by a deficiency of clotting factor VIII.

Cited by 1 publication

References 14 publications

The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome

The Risk of Venipuncture in Newborn with Severe Hemophilia: Case Report of a Large Elbow Hemorrhage and Literature Review of Compartment Syndrome

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