Large expansion of plasma commensal viruses is associated with SIV pathogenesis in
Macaca leonina
Yanpeng Li,
Tian-Zhang Song,
Le Cao
et al.
Abstract:Human immunodeficiency virus-1 (HIV-1) infection disrupts the homeostatic equilibrium between the host and commensal microbes. However, the dynamic changes of plasma commensal viruses and their role in HIV/simian immunodeficiency virus (SIV) pathogenesis are rarely reported. Here, we investigated the longitudinal changes of plasma virome, inflammation levels, and disease markers using an SIV-infected
Macaca leonina
model. Large expansions of plasma
Anelloviridae
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