Large eccrine angiomatous hamartoma: a novel clinical presentation of disease

Nygaard, Uffe; Dalager, Søren; Spaun, Eva; Hedelund, Lene

doi:10.3315/jdcr.2015.1211

Cited by 6 publications

(5 citation statements)

References 13 publications

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“…Non-surgical treatment options include the use of topical antiperspirants or intralesional injections of botulinum toxin in cases of hyperhidrosis. Additionally, laser therapy has been attempted but with little success [ 3 , 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Eccrine Angiomatous Hamartoma With Arteriovenous Malformation: A Rare Entity Re-Explored

Al-Zaidi¹,

Alotaibi²,

Aljuaid³

2022

Cureus

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Eccrine angiomatous hamartoma (EAH) is a rare, benign, slow-growing cutaneous lesion characterized by hamartomatous proliferation of the eccrine glands and vascular structures. It usually arises in early childhood; however, cases in adults have also been reported. It is diagnosed based on the clinical features of the lesion as well as the histopathological findings of the excised tissue. As the name indicates, EAH shows a close association with mature eccrine elements and capillary-sized blood vessels at the histopathological level. In rare instances, the vascular component can show the features of arteriovenous malformations. Here, we report a rare case of EAH with a component of arteriovenous malformation in a 39-year-old woman who presented with a foot lesion.

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Section: Discussionmentioning

confidence: 99%

Eccrine Angiomatous Hamartoma With Arteriovenous Malformation: A Rare Entity Re-Explored

Al-Zaidi¹,

Alotaibi²,

Aljuaid³

2022

Cureus

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“…The maximum anhidrotic effect was maintained until the week 30 after the treatment, then sweating relapsed, and 4-6 weeks later patient worsened to a condition requiring a new treatment. BoNT-A injection therapy has proved to be effective also in the eccrine angiomatous hamartoma [108]. Despite the rarity of EN, in selected cases, botulinum toxin represents a valid therapeutic option for patients suffering from this condition.…”

Section: Eccrine Nevusmentioning

confidence: 99%

Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review

Martina

Diotallevi

Radi

et al. 2021

Toxins

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Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis. Recently, botulinum toxins have also been used in many other skin diseases, in off label regimen. The objective of this manuscript is to review and analyze the main therapeutic applications of botulinum toxins in skin diseases. A systematic review of the published data was conducted, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Botulinum toxins present several label and off-label indications of interest for dermatologists. The best-reported evidence concerns focal idiopathic hyperhidrosis, Raynaud phenomenon, suppurative hidradenitis, Hailey–Hailey disease, epidermolysis bullosa simplex Weber–Cockayne type, Darier’s disease, pachyonychia congenita, aquagenic keratoderma, alopecia, psoriasis, notalgia paresthetica, facial erythema and flushing, and oily skin. Further clinical trials are still needed to better understand the real efficacy and safety of these applications and to standardize injection and doses protocols for off label applications.

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“…In the treatment of eccrine angiomatous hamartoma, an injections therapy of BoNT-A is useful. 52 Despite the condition’s rarity, it is simple to see how critical it is for these people to have a viable therapy option.…”

Section: Role Of Bont In Dermatologymentioning

confidence: 99%

Utilities of Botulinum Toxins in Dermatology and Cosmetology

Naik¹

2021

CCID

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Botulinum toxin (BoNT) is a neurotoxin produced by the Clostridium botulinum bacterium with a well-known efficacy and safety profile in the focal idiopathic hyperhidrosis treatment. BoNT comprises seven different neurotoxins; however, only toxins A and B are clinically employed. BoNT is lately practiced in off-label therapies for a variety of skin diseases. Scar prevention, hyperhidrosis, rhytides, eccrine nevus, alopecia, psoriasis, Darier disease, bullous skin disease, pompholyx and Raynaud’s phenomenon are some of the novel indications for BoNT in cosmetic and notably non-cosmetic aspects of dermatology. To employ BoNT correctly in clinical practice, we must have a thorough understanding of the functional anatomy of the mimetic muscles. An intensive literature search was conducted to update all dermatology-oriented experiments and clinical trials on the described element of BoNT for this general overview of BoNT use in dermatology. This review aims to analyse the role of BoNT in dermatology and cosmetology.

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Large eccrine angiomatous hamartoma: a novel clinical presentation of disease

Cited by 6 publications

References 13 publications

Eccrine Angiomatous Hamartoma With Arteriovenous Malformation: A Rare Entity Re-Explored

Eccrine Angiomatous Hamartoma With Arteriovenous Malformation: A Rare Entity Re-Explored

Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review

Utilities of Botulinum Toxins in Dermatology and Cosmetology

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