Large Cystic Intracardiac Mass Overlying Left Atrial Appendage Occlusion Device: A Case Report and Literature Review

Emerging Concepts on Infection of Novel Cardiac Implantable Devices

“…Five cases of LAA closure device endocarditis have been reported in the literature to date (Table 3 ) [ 73 , 74 , 75 , 76 , 77 ]. Median age of these cases was 74 years (range: 70–83) and onset of the infection was at a median of 140 days (range 6–900 days) after implantation.…”

“…In the latter patient, neurologic manifestations were a consequence of cerebral embolism, whereas another patient had detectable although asymptomatic cerebral emboli. One patient also received a diagnosis of osteomyelitis of the great toe [ 77 ].…”

“…One patient developed hemothorax, encephalopathy, respiratory failure requiring tracheostomy, and occlusive thrombosis of the right axillary vein after surgery [ 75 ]. Four patients (80%) [ 73 , 75 , 76 , 77 ] were discharged alive, while the fifth died of cardiogenic shock (surgical case). Postoperatively, 1 patient (33%) [ 74 ] developed brainstem stroke that resolved within 24 h with residual generalized weakness and disability; another patient (not operated on) underwent lifelong suppressive antibiotic therapy [ 76 ].…”