Large cell neuroendocrine carcinoma primarily in the pericardium: a case report and literature review

Yin, Yue; Zhang, Yun; Huo, Zhen; Ma, Guotao; Ma, Yu; Zhang, Xuejun

doi:10.1097/cm9.0000000000000586

Chinese Medical Journal

2019

DOI: 10.1097/cm9.0000000000000586

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Large cell neuroendocrine carcinoma primarily in the pericardium: a case report and literature review

Yue Yin

Yun Zhang

Zhen Huo

et al.

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2023

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“…Furthermore, SDHB gene mutations could influence the diagnostic performance of 18 F-DOPA PET or PET/CT. 62 68 Ga-DOTATOC-PET/CT and 18 F-FDG-PET/CT are established imaging modality for identifying cardiac metastases in NETs, 38,55,64 and in the rare case of imaging metastases either in the myocardium or in the pericardium, where they have a complementary role, as well as in the demonstration of the extent of NET disease.…”

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confidence: 99%

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Hybrid imaging of neuroendocrine tumors in the heart: Union is strength

Marketou

Kapsoritakis

Bourogianni

et al. 2023

Journal of Nuclear Cardiology

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Cardiac neuroendocrine tumors (NETs) are particularly rare tumors that can lead to a very poor clinical outcome, partly because of metastases but mainly because of manifestations of the hormonal activity they exhibit. Prompt diagnosis is important in order to start the most effective treatment for their removal or management, with the fewest complications. They are often difficult to diagnose, especially in their early stages. One of the reasons for this is that the heart is an organ with a high rate of metabolism and is located in close proximity to other highmetabolism organs. In addition, the anatomic location and their small size render their diagnosis extremely challenging. In recent years, hybrid imaging methods have revolutionized the diagnostic approach to oncology patients and have established a place in the diagnosis of cardiac NETs, because they provide both anatomical and functional information at the same time. Positron emission tomography/computed tomography (PET/CT), PET/magnetic resonance imaging (PET/MRI) and single-photon emission computed tomography/CT (SPECT/CT) are widely used in clinical practice because of the very important metabolic information, the high sensitivity and specificity. However, prospective studies are needed to confirm the true clinical and prognostic value of various hybrid imaging diagnostic techniques in cardiac NETs.

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confidence: 99%

“…unphosphorylated) 18 F-FDG. 17,64 PET/MRI PET/MRI can provide a comprehensive imaging evaluation of cardiac NETs. MRI has better imaging resolution in soft tissue, with consistency in clinical practice.…”

mentioning

confidence: 99%

Hybrid imaging of neuroendocrine tumors in the heart: Union is strength

Marketou

Kapsoritakis

Bourogianni

et al. 2023

Journal of Nuclear Cardiology

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Large cell neuroendocrine carcinoma primarily in the pericardium: a case report and literature review

Cited by 1 publication

References 5 publications

Hybrid imaging of neuroendocrine tumors in the heart: Union is strength

Hybrid imaging of neuroendocrine tumors in the heart: Union is strength

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