Laparoscopic surgery vs laparotomy for early stage endometrial cancer: long-term data of a randomized controlled trial

Comparison of laparoscopic versus conventional open surgical staging procedure for endometrial cancer

“…13 Although several authors have reported on the feasibility and safety of the laparoscopic surgery in early-stage endometrial cancer compared with open surgery, there is no general agreement as to whether laparoscopic treatment for endometrial cancer is comparable to laparotomy in terms of survival, because of lack of sufficient survival data. [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Recently,…”

An analysis of current treatment practice in uterine papillary serous and clear cell carcinoma at two high-volume cancer centers

“…While we did not find www.ejgo.org 29 a therapeutic effect of paraaoritc lymphadenectomy in our high-risk patient cohort, a role for comprehensive surgical staging may be beneficial, in particular in further guiding adjuvant therapy and discussing prognosis. While there have been several studies evaluating the role of minimally invasive surgical staging in endometrial cancer, including the LAP2 trial, there have been very few evaluating patients of high risk histology (i.e., with UPSC or UCCC) [7,8,[17][18][19]. Fader et al [9] evaluated both a traditional and minimally invasive surgical staging approach in patients with UPSC, UCCC and grade 3 endometrioid adenocarcinoma and noted similar, favorable results for laparoscopic/robotic surgical staging.…”

The Modern Surgical Strategy for Endometrial Cancer: Laparoscopic Surgery

“…Only four RCTs have reported quality of life (QOL) data for patients undergoing either laparoscopic or laparotomy [36,37,39,42,43••]. Zullo et al performed QOL assessments at baseline, at 1, 2, and 6 months, and then annually for 7 years after surgery [36,37].…”

“…Zullo et al performed QOL assessments at baseline, at 1, 2, and 6 months, and then annually for 7 years after surgery [36,37]. Laparoscopic surgery was associated with a significantly better QOL for the first 3 years after surgery, after which time no difference was noted.…”

“…Indeed, whilst endometrial cancer is the first gynecologic cancer to be treated laparoscopically, a laparoscopic approach also is being used for the surgical management of malignant disease. Following the first report on the use of laparoscopic surgery for endometrial cancer by Childers et al [12], the feasibility, safety, and efficacy of laparoscopic surgery in the surgical management of endometrial cancer has been reported in numerous retrospective studies [13][14][15][16][17][18][19][20][21][22][23][24][25], prospective nonrandomized studies [26][27][28][29], or randomized, controlled trials (RCTs) [30][31][32][33][34][35][36][37][38][39][40][41][42]43 This review provides an update on the role of laparoscopic surgery for the surgical management of endometrial cancer with particular emphasis on feasibility, safety, and efficacy based on the results of randomized, controlled trials comparing laparoscopy and laparotomy for surgical staging of endometrial cancer.…”