Laparoscopic splenectomy for non-Hodgkin lymphoma

Walsh, R. Matthew; Heniford, B. Todd

doi:10.1002/(sici)1096-9098(199902)70:2<116::aid-jso10>3.0.co;2-y

Cited by 30 publications

(26 citation statements)

References 26 publications

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“…In nonHodgkin's lymphoma, splenic involvement occurs in 35% to 80% of cases and typically presents with symptoms of splenomegaly and hypersplenism [4,27,35]. Occasionally, non-Hodgkin's lymphoma presents with isolated splenic involvement [43]. In chronic lymphocytic leukemia, splenomegaly may be one of the earliest findings [43].…”

Section: Discussionmentioning

confidence: 99%

“…Occasionally, non-Hodgkin's lymphoma presents with isolated splenic involvement [43]. In chronic lymphocytic leukemia, splenomegaly may be one of the earliest findings [43]. In hairycell leukemia, splenomegaly may be the major finding, and subsequent splenectomy is associated with lasting remission [5].…”

Section: Discussionmentioning

confidence: 99%

“…Operative technique with the patient in the lateral position previously has been described extensively [32,43]. At least 1 week before surgery, patients receive a polyvalent pneumococcal, meningococcus, and Haemophilus influenzae vaccine, and prophylactic antibiotics are given immediately before surgery.…”

Section: Methodsmentioning

confidence: 99%

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Outcome of laparoscopic splenectomy based on hematologic indication

et al. 2001

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When performed for ITP, laparoscopic splenectomy resulted in shorter operations, minimal blood loss, earlier discharge, no conversions, and excellent remission rates, as compared with other hematologic indications. Despite larger spleens, more blood loss, and longer operations in patients with hematologic malignancies, morbidity and length of hospital stay still were similar to those associated with benign indications for laparoscopic splenectomy. In conclusion, laparoscopic splenectomy is safe and efficacious for a multitude of benign and malignant hematologic indications, and our data compares favorably to those for open series.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Outcome of laparoscopic splenectomy based on hematologic indication

et al. 2001

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“…In spite of the lack of studies with long-term follow-up, LS seems to provide similar results to OS in relation to hematological disease, mainly in ITP (Table 5) [60,61,62,63,64,65]. Recent studies highlight the interest in LS for treatment of hematological malignancies requiring splenectomy [66,67]. Furthermore, preliminary data suggest that cost for LS will ultimately equal or may even be less than open surgery (Table 6) Targarona (1990 [57] Park (1994)(1995)(1996)(1997)(1998) [ of similar age, weight, height, and type of complication.…”

Section: Ls and The Accessory Spleenmentioning

confidence: 98%

Laparoscopic surgery of the spleen: state of the art

Park

Targarona

Trías

2001

Langenbeck's Arch Surg

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Although LS continues to pose certain technical challenges--such as management of the massive spleen, specimen extraction, and identification of remotely located accessory spleens--its advantages over OS in terms of faster postoperative recovery, shorter hospital stay, and equivalent or lower perioperative morbidity are now well established. Indications for LS and more laparoscopic spleen-conserving surgery are likely to broaden.

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“…Inicialmente ela era considerada uma contra-indicação, mas a curva de aprendizado e a melhoria técnica alteraram esta situação 8,15 . Walsh et al 16 . descreveram que a EL é factível e segura mesmo na esplenomegalia associada a linfomas .…”

Section: Esplenectomia (N = 40)unclassified

Esplenectomia laparoscópica nas doenças hematológicas

Melo-Filho

Miranda

Pinheiro

et al. 2003

Rev. Col. Bras. Cir.

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RESUMO: Objetivo:Relatar a experiência inicial do Centro Infantil Boldrini com a esplenectomia laparoscópica (EL) em crianças e adultos jovens. Método: Foram revisados os prontuários de 40 pacientes (mediana da idade de 6,6 anos; 1 a 22,8) submetidos à EL entre Julho de 2000 e Maio de 2002. As principais indicações de acordo com a doença de base foram: doença falciforme (DF) em 20 pacientes (50%), esferocitose hereditária em 10 (25 %), púrpura trombocitopência idiopática em oito (20 %), doença de Hodgkin em um e anemia hemolítica a esclarecer em um. Resultados: Trinta e oito esplenectomias foram completadas por via laparoscópica (duas conversões) e em doze foi realizada adicionalmente a colecistectomia. A mediana do tempo operatório foi de 127,5 minutos (90 -240 min) e sete (17,5 %) baços acessórios foram encontrados. Sangramento intra-operatório foi significativo apenas nas duas conversões, mas não houve necessidade de transfusões. A mediana do peso dos baços foi de 250 g (106 -1000; n=36). Complicações pós-operatórias ocorreram em sete (17,5 %) pacientes e, nos portadores de DF, 35% desenvolveram síndrome torácica aguda. A mediana da permanência hospitalar pós-operatória foi de dois dias (2 -14). O seguimento variou de 23 dias a dois anos (mediana de 11 meses). Conclusões: A EL pode ser realizada de modo seguro mesmo em baços de grande tamanho e é opção atrativa que pode substituir o procedimento aberto. Em pacientes com DF, a taxa de complicações permanece alta, sugerindo mecanismos outros que vão além da escolha da via de acesso cirúrgica.

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Laparoscopic splenectomy for non-Hodgkin lymphoma

Cited by 30 publications

References 26 publications

Outcome of laparoscopic splenectomy based on hematologic indication

Outcome of laparoscopic splenectomy based on hematologic indication

Laparoscopic surgery of the spleen: state of the art

Esplenectomia laparoscópica nas doenças hematológicas

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