Laparoscopic sleeve gastrectomy for weight loss and treatment of type 2 diabetes mellitus

Abstract

Objectives Weight loss is a key component in the management of type 2 diabetes mellitus (T2DM). This outcome can be potentially achieved by laparoscopic sleeve gastrectomy (LSG). This study aims to determine the efficacy of LSG in reducing weight and to evaluate its impact on controlling T2DM by measuring HbA1c and body mass index (BMI) preoperatively and during the first year following the procedure. Methods This retrospective study was carried out on 340 patients aged ≥15 years who had T2DM and a BMI of ≥ 35 kg/m 2 . These patients had LSG at King Fahad Hospital Almadinah Almunawwarah KSA between January 2015 and July 2019. Their HbA1c and BMI were measured preoperatively and then postoperatively at less than one month, 1–3, 4–6, 7–9, and 10–12 months as well as after one year. Results Average BMI dropped consistently from a preoperative BMI of 49.27 kg/m 2 to 32.72 kg/m 2 at 10–12 months following LSG. A reduction in HbA1c from 8.38% to 6.43% was observed over one year ( p = 0.0001). Seventy-five percent of the patients achieved the HbA1c target of 6.5% or less within one year. The remaining 25% of the patients showed improvement in their HbA1c but did not reach the target level. Conclusion This study endorses a positive impact of LSG on both weight loss and diabetic status. There was a significant reduction of both BMI (up to the first year) and HbA1c levels postoperatively.

Glycemic Control in the era of bariatric surgery: A systematic review and meta-analysis of published studies on the Saudi-Arabian population

“…Finally, three studies were involved. [ 1 14 15 ] The three studies were included in our analysis, Figure 1 . The summary and baseline characteristics of randomized controlled trials (RCTs) are mentioned in Tables 1 and 2 .…”

“…Three trials[ 1 14 15 ] studied the effect of LSG and RYGB on BMI, and a total of 760 patients were enrolled in those three trials. Results were significant as seen [mean difference (MD) 1.54; CI 0.76–2.32; P value 0.0001].…”

The Effect of Laparoscopic Sleeve Gastrectomy on the Course of Non-Alcoholic Fatty Liver Disease in Morbidly Obese Patients during One Year of Follow Up

“…However, very often, the above recommendations are difficult to fulfill, and obese patients fail to achieve the expected weight loss. Several studies have shown that laparoscopic sleeve gastrectomy causes significant weight loss over both short- and long-term observation periods [ 17 , 18 , 19 ]. Kraljević et al analyzed 307 patients who underwent LSG as a primary bariatric procedure.…”

Evaluating Laparoscopic Sleeve Gastrectomy for Morbid Obesity: A Prospective Follow-Up Study

“…LSG has garnered attention for its effectiveness in achieving weight loss, with patients typically experiencing a reduction of 50% to 70% of excess weight within the initial postoperative year [ 9 ]. Furthermore, LSG shows beneficial outcomes in addressing obesity-related comorbidities like type 2 diabetes and hypertension, while also presenting a lower risk profile compared to alternative surgical methods [ 10 ].…”