Laparoscopic Resection of a Retroperitoneal Degenerative Schwannoma: A Case Report and Review of the Literature

Pinto, David; Kaidar‐Person, Orit; Cho, Minyoung; Zundel, Nathan; Szomstein, Samuel; Rosenthal, Raúl J.

doi:10.1097/sle.0b013e3181581fab

Cited by 17 publications

(23 citation statements)

References 13 publications

(19 reference statements)

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“…They are also insensitive to chemotherapy and radiotherapy. 2,5,8,9 In general, preoperative biopsies are not recommended for these lesions by most authors. However, Schindler et al 6 regarded needle biopsy as the diagnostic gold standard and Hughes et al 7 used core biopsy combined with imaging features to decide on conservative nonsurgical management.…”

Section: Discussionmentioning

confidence: 99%

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

Shabiyullah¹,

Singaporewalla²,

Rao³

et al. 2014

World Journal of Endocrine Surgery

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Schwannomas are rare tumors originating from Schwann cells of peripheral nerve sheath (neurilemma) of the ectoderm. They are also referred to as neurilemmomas and are generally be nign, solitary tumors arising from cranial and peripheral nerves. Rarely, they arise from the retroperitoneum and adrenal medulla. Retroperitoneal schwannomas constitute about 0.5 to 5% of all schwannomas and of which most of them are benign in nature. Most patients are asymptomatic or have vague abdominal symp toms. On imaging, they are often mistaken for adrenal tumors due to their location and preoperative diagnosis is often difficult. Magnetic resonance imaging (MRI) is the investigation of choice to demonstrate these lesions and its relation to other structures. Total excision is recommended as malignancy, although rare cannot be ruled out preoperatively. We present a case of a large retroperitoneal schwannoma that mimicked an adrenal incidentaloma and was excised laparoscopically. The imaging characteristics and management strategy are discussed.

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Section: Discussionmentioning

confidence: 99%

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

Shabiyullah¹,

Singaporewalla²,

Rao³

et al. 2014

World Journal of Endocrine Surgery

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“…T�ey ��e o�din��i�y seen in ��e �e�d, neck, �nd exi�y seen in ��e �e�d, neck, �nd exseen in ��e �e�d, neck, �nd ex� tremities�� an�� are on�� rare�� oun�� in the retro�eritone� um; � �e��o�e�i�one�� oc��ion �ccoun�ed �o� 0.3%-3.2% 3%-3.2% -3.2% 3.2% % o� a�� rimar� schwannomas [2][3][4][5][6] 6] �nd 0.3%-6.0% o� �� 0.3%-6.0% o� �� retro�eritonea�� tumors [7][8][9][10][11][12] . �s ��evious�y desc�ibed, �� indings o� sc��nnom�s gene��y s�o� � �e��-defined �y�oec�oic m�ss �i�� s�ig��y �e�e�ogeneous in�e�n�� ec�o �eve�.…”

Section: Discussionmentioning

confidence: 99%

Three cases of retroperitoneal schwannoma diagnosed by EUS-FNA

Kudo

Kawakami²,

Kuwatani³

et al. 2011

WJG

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Schwannomas are peripheral nerve tumors that are typically solitary and benign. Their diagnosis is largely based on surgically resected specimens. Recently, a number of case reports have indicated that retroperito� neal schwannomas could be diagnosed with endoscopic endoscopic ultrasound�guided fine�needle aspiration �E�S�FNA�.�guided fine�needle aspiration �E�S�FNA�. �needle aspiration �E�S�FNA�. needle aspiration �E�S�FNA�. We report the diagnosis of three cases of schwannoma using E�S�FNA. Subjects were two males and one fe� two males and one fe� wo males and one fe� male, ages 22, 40, and 46 years, respectively, all of whom were symptom�free. Imaging findings showed well�circumscribed round tumors. However, as the s. However, as the . However, as the tumors could not be diagnosed using these findings alone, E�S�FNA was performed. Hematoxylin�eosin staining of the resulting tissue fragments revealed bland spindle cells with nuclear palisading. There was no disparity in nuclear sizes. Immunostaining revealed nuclear sizes. Immunostaining revealed nuclear sizes. Immunostaining revealed S�100 protein positivity and all cases were diagnosed as schwannomas. Ki�67 indexes were ��1��, 2��, es were ��1��, 2��, were ��1��, 2��, and ��, respectively. No case showed any signs of ma� lignancy. As most schwannomas are benign tumors and ost schwannomas are benign tumors and schwannomas are benign tumors and benign tumors and benign tumors and s and and seldom become malignant, we observed these patients without therapy. All tumors demonstrated no enlarge� no enlarge� enlarge� ment and no change in characteristics. Schwannomas and no change in characteristics. Schwannomas no change in characteristics. Schwannomas are almost always benign and can be observed follow� ing diagnosis by E�S�FNA. Key words: Schwannoma; Endoscopic ultrasonography; ndoscopic ultrasonography; ultrasonography; ltrasonography; nography; Fine�needle aspiration; Retroperitoneal tumor; S100 ine�needle aspiration; Retroperitoneal tumor; S100 �needle aspiration; Retroperitoneal tumor; S100 needle aspiration; Retroperitoneal tumor; S100 ; Retroperitoneal tumor; S100 proteins; Ki�67 index

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“…Histologically, schwannomas show two different patterns: Antoni A (AA)-dense cellularity aggregation of fibrillary, elongated cells-and Antoni B (AB)-low cellularity poorly organized tissue rich in cystic spaces [2,5]. Verocay bodies (fusiform cells arranged in whorls or palisades), hyalinized/ectatic vessels with hemosiderin deposits, and encapsulation by residual collagenous perineurium can also be recognized [7].…”

Section: Introductionmentioning

confidence: 97%

“…Retroperitoneal schwannomas account for 0.5-3% of retroperitoneal tumors in most series, but up to 21% of retroperitoneal tumors in some series from specialized centers [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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A large pelvic mass in a 39-year-old man

et al. 2011

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Schwannomas are encapsulated, usually benign, tumors composed of well-differentiated Schwann cells, arising from the neural sheath of peripheral nerves. The most common type of benign schwannoma is the acoustic neuroma arising from the eighth cranial nerve. Retroperitoneal schwannomas account for 0.5-3% of the retroperitoneal tumors in most series. We present a case of a 39-year-old man with a pelvic mass, arising from a sacral nerve root, diagnosed as a schwannoma.

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Laparoscopic Resection of a Retroperitoneal Degenerative Schwannoma: A Case Report and Review of the Literature

Cited by 17 publications

References 13 publications

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

Retroperitoneal Schwannoma mimicking a Large Adrenal Incidentaloma: Case Report and Review of Literature

Three cases of retroperitoneal schwannoma diagnosed by EUS-FNA

A large pelvic mass in a 39-year-old man

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