Laparoscopic radical prostatectomy for high risk localized and locally advanced disease

Tobias-Machado, Marcos; Starling, E.; Carlos, Alexandre Stievano; Pompeo, Antônio Carlos Lima; Romanelli, Pedro; Nishimoto, Ricardo Hissashi

doi:10.1590/s1677-55382012000300019

Int. braz j urol.

2012

DOI: 10.1590/s1677-55382012000300019

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Laparoscopic radical prostatectomy for high risk localized and locally advanced disease

Marcos Tobias-Machado¹,

E. Starling²,

Alexandre Stievano Carlos³

et al.

Abstract: Laparoscopic surgery adopting oncological principles can be utilized with efficacy to selected patients with high risk localized and locally advanced prostate cancer maintaining the advantages of minimally invasive surgical approach.

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Comparison of positive surgical margin rates in high risk prostate cancer: open versus minimally invasive radical prostatectomy

Harty¹,

Kozinn²,

Canes³

et al. 2013

Int. braz j urol.

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Objective: We compared positive surgical margin (PSM) rates for patients with high risk prostate cancer (HRCaP) who underwent open radical retropubic (RRP), robotic (RALP), and laparoscopic (LRP) prostatectomy at a single institution. Materials and Methods:We performed a retrospective review of our prospectively maintained IRB approved database identifying prostate cancer patients who underwent RRP, RALP, or LRP between January 2000 and March 2010. Patients were considered to have HRCaP if they had biopsy or final pathologic Gleason score ≥ 8, or preoperative PSA ≥ 20, or pathologic stage ≥ T3a. A positive surgical margin (PSM) was defined by the presence of tumor at the inked surface of the specimen. Patients who received neoadjuvant hormonal therapy and those who underwent a perineal prostatectomy were excluded from the study. Results: Of the 445 patients in this study, surgical technique for prostatectomy included RRP (n = 153), RALP (n = 152), and LRP (n = 140). PSM rate for the three groups were not different: 52.9% RRP, 50% RALP, and 41.4% LRP, (p = 0.13). The PSM rate did not differ when comparing RRP to a combined group of RALP and LRP (p = 0.16). Among patients with a PSM, there was no statistical difference between the three groups in terms of the number of patients with a pathologic stage of T3 or higher (p = 0.83). On univariate analysis, a higher preoperative PSA value was associated with a positive margin (p = 0.04). Conclusion: In this HRCaP series, the PSM rate did not differ based on the surgical approach. On univariate analysis, patients with a higher preoperative PSA value were more likely to have a PSM.

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Comparison of positive surgical margin rates in high risk prostate cancer: open versus minimally invasive radical prostatectomy

Harty¹,

Kozinn²,

Canes³

et al. 2013

Int. braz j urol.

View full text Add to dashboard Cite

show abstract

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Laparoscopic radical prostatectomy for high risk localized and locally advanced disease

Abstract: Laparoscopic surgery adopting oncological principles can be utilized with efficacy to selected patients with high risk localized and locally advanced prostate cancer maintaining the advantages of minimally invasive surgical approach.

Cited by 1 publication

References 0 publications

Comparison of positive surgical margin rates in high risk prostate cancer: open versus minimally invasive radical prostatectomy

Comparison of positive surgical margin rates in high risk prostate cancer: open versus minimally invasive radical prostatectomy

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