Laparoscopic Nissen Fundoplication: Clinical Outcomes at 10 Years

Kelly, Jamie; Watson, David I.; Chin, Kin-Fah; Devitt, Peter G.; Game, Philip A.; Jamieson, Glyn G.

doi:10.1016/j.jamcollsurg.2007.05.024

Cited by 109 publications

(78 citation statements)

References 22 publications

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“…28% nehmen wieder säuresuppressive Medikamente ein. Im Vergleich mit Studien mit kürzerer Nachbeobachtungszeit ist diese Rate relativ hoch [2,15], in Studien mit vergleichbaren Beobachtungszeiten fanden sich jedoch zum Teil deutlich höhere Rezidivraten [17,21]. 62% der operierten Patienten einer randomisierten Studie zum Vergleich der offenen Antirefluxoperation mit konservativer Therapie hatten im Langzeitverlauf wieder säure-suppressive Medikamente eingenommen [23].…”

Section: Ppi H2-blocker Antacidaunclassified

“…Gleichzeitig war eine Dysphagie bei der Vollmanschette auch bei schlechter Ösophagusperistaltik nicht häufiger [22]. Allerdings wurde bisher nur selten über Ergebnisse mehr als 10 Jahre nach laparoskopischer Fundoplikation berichtet [3,4,17].Vor diesem Hintergrund wurden die 10-Jahres-Ergebnisse unserer Patienten nach laparoskopischer Antirefluxoperation ausgewertet. Primärer Endpunkt war die Refluxrezidivrate.…”

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Weniger Refluxrezidive nach Nissen-Fundoplikation

Fein

Bueter

Thalheimer

et al. 2008

Chirurg

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Section: Ppi H2-blocker Antacidaunclassified

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Weniger Refluxrezidive nach Nissen-Fundoplikation

Fein

Bueter

Thalheimer

et al. 2008

Chirurg

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“…The main objectives of the surgical treatment are the reduction of symptoms and improvement in qualityof-life. Patients reported good results after surgery, with significant reduction of symptoms in 80% to 95% on five to 10-year follow-up (2,7,8) . However, a significant number of patients have either recurrence of symptoms or the development of new symptoms that were not present before surgery, with impact on quality-of-life.…”

Section: Introductionmentioning

confidence: 95%

Improvement in Quality-of-Life After Laparoscopic Nissen Fundoplication

Kappáz

Sallum

Szachnowicz

et al. 2014

Arq. Gastroenterol.

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-Context -Evaluating quality of life after surgery for gastroesophageal reflux is fundamental, since improvement of symptoms is the main goal of treatment. Objective -To compare the satisfaction of patients operated for GERD, interviewed at the office, with patients interviewed by telephone. Methods -One hundred and seventy-eight patients were submitted to laparoscopic Nissen fundoplication. Ninety patients were found, and 45 agreed to come to the hospital's office. The other 45 patients were interviewed by telephone. Quality of life was evaluated using three methods: The GERD-HRQL questionnaire, translated to Portuguese; question "If you could choose it today, would you do surgery again?"; and question "If you could classify your symptom improvement between 0 and 10, which grade would you give?" Patients were divided in group A (office interview) and B (telephone interview). Statistical analysis was performed. Results -The average GERD-HRQL score in group A was 6.29, while in group B was 14.09 (P = 0.002). There was no statistical difference between groups A and B regarding patients choice of doing the surgery again (P = 0.714) and their grade of postoperative symptom improvement (P = 0.642). Conclusion -The overall postoperative satisfaction was high. The GERD-HRQL questionnaire might not be suitable for application by telephone in our population, and based on other analyzes, the satisfaction and quality of life of patients interviewed at the office or by telephone was similar. HEADINGS -Gastroesophageal reflux. Fundoplication. Quality of life.

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“…A study by Kelly et al demonstrated durability to 10 years when performed by an experienced surgeon [9].…”

Section: Laparoscopic Nissen Fundoplicationmentioning

confidence: 99%

Gastroesophageal Reflux Disease: Diagnosis and Patient Selection

Singhal

Khaitan

2014

Indian J Surg

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Gastroesophageal reflux disease (GERD) has a high prevalence worldwide. Recent reports have noted a high prevalence even in Asian countries. GERD significantly affects the quality of life and can present with a wide variety of symptoms. Not all reflux is acid, and non-acid reflux disease can be more difficult to diagnose and can lead to a variety of extra-esophageal symptoms. Although proton pump inhibitors (PPIs) are effective in the majority of patients, but they are not without side effects, and their effect often diminishes with time. For patients who do not desire to be on long-term PPIs or have incomplete symptom resolution with medication, various endoscopic and minimally invasive treatment modalities are now available. The etiology of GERD can be multifactorial including dysfunctional LES, presence of a hiatal hernia, and transient lower esophageal sphincter relaxations (TLESRs). We hence believe that the treatment should be individualized to the cause of the reflux. In the following review, we describe the etiology of reflux disease and attempt to lay a framework for the diagnosis and selection of patients for the various interventions available for treatment, along with their evidence base.

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Laparoscopic Nissen Fundoplication: Clinical Outcomes at 10 Years

Cited by 109 publications

References 22 publications

Weniger Refluxrezidive nach Nissen-Fundoplikation

Weniger Refluxrezidive nach Nissen-Fundoplikation

Improvement in Quality-of-Life After Laparoscopic Nissen Fundoplication

Gastroesophageal Reflux Disease: Diagnosis and Patient Selection

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