Laparoscopic excision of a retroperitoneal mucinous cystic neoplasm: A case report

Lung, John; Gracey, Allison; Rosales, Abigail; Bashover, Eva; Sbar, Alan; Nazim, Muhammad; Rico, Ferdinand

doi:10.1016/j.ijscr.2019.07.010

Cited by 4 publications

(9 citation statements)

References 10 publications

(9 reference statements)

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“…They have been rarely described in the mesentery [2]. The epidemiology of MCNs highlights a predominance in adult females [1,[3][4][5]. Histologically, MCNs are similar to ovarian mucinous neoplasms and are characterized by a mucinsecreting flat, columnar, or cuboidal epithelium associated with an underlying ovarian-like stroma [2,4].…”

Section: Discussionmentioning

confidence: 99%

A Symptomatic Mucinous Cystic Neoplasm of the Mesentery: A Case Report

Amy,

Roberts,

Arisi

et al. 2024

Cureus

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Mucinous cystic neoplasms (MCNs) are rare tumors primarily observed in the pancreas but occasionally found in other locations such as the retroperitoneum, ovary, liver, and spleen. These neoplasms are histologically classified based on the degree of dysplasia, with some associated with invasive carcinoma. Colorectal surgeons infrequently encounter MCNs. Mesenteric MCNs pose a diagnostic challenge secondary to their atypical location, subtle histology, and lack of specific biochemical markers. In this context, we present a case involving a 68-year-old female who initially presented with an assumed ovarian mass. Subsequent exploration revealed a 12 cm MCN situated in the sigmoid mesentery, a location seldom associated with these tumors. The patient underwent laparotomy with successful resection and recovery. Histopathological analysis confirmed the neoplasm's mucinous epithelium with a complex papillary architecture. Immunohistochemical staining supported the diagnosis, revealing positivity for CK7, SATB2, and CDX2.

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Section: Discussionmentioning

confidence: 99%

A Symptomatic Mucinous Cystic Neoplasm of the Mesentery: A Case Report

Amy,

Roberts,

Arisi

et al. 2024

Cureus

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“…The first one argues that PRMCs are believed to be originating from heterotopic ovarian tissue due to its sound resemblance to ovarian cystadenomas. The second hypothesis considers PRMCs to originate from an invagination of the mesothelium of the peritoneum that becomes experiences mucinous metaplasia and forms as a cyst 11 , 12 .…”

Section: Discussionmentioning

confidence: 99%

“…These four cases are in chronological order as follows: Lung J. et al . 11 , Danen C. et al . 22 , Dorji N. et al .…”

Section: Discussionmentioning

confidence: 99%

An enormous benign primary retroperitoneal mucinous cystadenoma: a case report and literature review of a seldom seen abdominal pathology

Al Laham,

Adi,

Alaitouni

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Retroperitoneal neoplasia comprise less than 2% of all tumours. benign primary retroperitoneal mucinous cystadenoma (PRMC) is an extremely rare tumour. Their clinical course is overall silent unless the patient presents with a vague abdominal or pelvic pain, abdominal distention, or a palpable mass. Their aetiology remains theorized and since 1989, only 46 cases (excluding ours) worldwide were documented in the literature. The majority of cases were discovered in females but the overall tumour incidence rate is still undetermined due to its rarity. Well-timed recognition of this pathology permits the necessary curative surgical intervention to take place. Case presentation: We hereby illustrate the rare case of a 23-year-old female who presented to the surgical clinic complaining solely of an unexplained gradual increase of the abdominal contour. Their presurgical radiological analysis yielded an intraabdominal large-sized well-demarcated retroperitoneal mass. Clinical discussion: Thorough resection of the mass was accomplished via open surgery. The subsequent microscopic analysis of excised tumour yielded the diagnosis of primary retroperitoneal mucinous cystadenoma of benign nature. Conclusion: Primary retroperitoneal mucinous cystadenoma is a seldom seen tumour. The scarcity of its occurrence is further highlighted by the published data. Based on their conclusive review of the available published English-based literature, ours is the 47th documented case of a benign PRMC and it is the first documented case from our country; Syria. The impact of these findings warrants raising awareness on the subject and considering PRMC as a differential diagnosis when presented with a similar case in the clinical practice.

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“…Estrogen receptor positivity in stromal cells of PRMCs has also been indicated. Second, these tumors arise from an invagination of peritoneal mesothelium that is entrapped and undergoes mucinous metaplasia and cyst formation [5] , [6] . Generally, cysts are asymptomatic and are found fortuitously after a routine checkup assessment.…”

Section: Discussionmentioning

confidence: 99%

“…This type is similar to the ovarian mucinous cystadenomas of low malignant potential. The third type is the mucinous cystadenocarcinoma that is an invasive tumor [5] , [6] .…”

Section: Discussionmentioning

confidence: 99%