Laparoscopic colectomy and restorative proctocolectomy for familial adenomatous polyposis

Vitellaro, Marco; Bonfanti, G.; Sala, Paola; Barisella, Marta; Signoroni, Stefano; Mancini, Andrea; Bertario, Lucio

doi:10.1007/s00464-010-1478-z

Cited by 34 publications

(33 citation statements)

References 48 publications

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“…Prophylactic colectomy is recommended to prevent the early onset of CRC in FAP patients. [62][63][64] Laparoscopic approach has been reported to have acceptable short-and long-term postsurgical and oncological outcomes: for adolescents this can support the decision making for prophylactic surgery in FAP patients reducing the risk of cancer. 65 In LS, usually a segmental resection is performed, and the genetic mutation is identified after the primary surgery.…”

Section: Discussionmentioning

confidence: 95%

Gastrointestinal tract carcinoma in pediatric and adolescent age: The Italian TREP project experience

Indini

Bisogno

Cecchetto

et al. 2017

Pediatric Blood & Cancer

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Section: Discussionmentioning

confidence: 95%

Gastrointestinal tract carcinoma in pediatric and adolescent age: The Italian TREP project experience

Indini

Bisogno

Cecchetto

et al. 2017

Pediatric Blood & Cancer

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“…These risks can be prevented by close rectal wall dissection and a laparoscopic approach [52]. The laparoscopic approach, which gives a better cosmetic result, has proven to be superior to laparotomy [53]. Further advantages of laparoscopic TPC-IPAA are associated with less adhesion formation, which reduces risks of small bowel obstruction.…”

Section: Polyposis Syndromesmentioning

confidence: 99%

Colorectal polyps and polyposis syndromes

Shussman

Wexner

2014

Gastroenterology Report

164

122

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A polyp is defined as any mass protruding into the lumen of a hollow viscus. Colorectal polyps may be classified by their macroscopic appearance as sessile (flat, arising directly from the mucosal layer) or pedunculated (extending from the mucosa through a fibrovascular stalk). Colorectal polyps may also be histologically classified as neoplastic or as non-neoplastic (hyperplastic, hamartomatous, or inflammatory). The neoplastic polyps are of primary importance because they harbor a malignant potential, which represents a stage in the development of colorectal cancer. For this reason, it is essential to identify these polyps at a sufficiently early stage, when a simple outpatient procedure to remove them can interrupt the development of colorectal cancer and prevent disease and death. When invasive carcinoma arises in a polyp, careful consideration must be given to ensuring the adequacy of treatment. Although most neoplastic polyps do not evolve into cancer, it is well accepted that the majority of colorectal carcinomas evolve from adenomatous polyps; the sequence of events leading to this transformation is referred to as the adenoma-to-carcinoma sequence.The presence of a systemic process that promotes the development of multiple gastro-intestinal polyps is termed ‘polyposis’. Hereditary gastro-intestinal polyposis syndromes account for approximately 1% of all cases of colorectal cancer and are associated with a broad spectrum of extra-colonic tumors. Early detection and accurate classification of these syndromes are essential, in order to initiate a surveillance program for the early detection of cancer. Several polyposis syndromes have been described, each having its own genetic basis and characteristic polyp distribution, clinical presentation, and malignancy risk.Diagnostic modalities and treatment options for neoplastic polyps—as well as the most prevalent polyposis syndromes—are reviewed below.

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“…Laparoscopic IPAA has been shown to be safe when compared with open surgery . Larson et al presented a case‐matched series of 300 patients with 100 laparoscopic cases demonstrating earlier return of bowel function, reduced requirements for narcotics and equivalent complication rates .…”

Section: Does Laparoscopic Colectomy Increase the Risk Of Desmoid Dismentioning

confidence: 99%

“…35 Laparoscopic IPAA has been shown to be safe when compared with open surgery. 44 Larson et al presented a case-matched series of 300 patients with 100 laparoscopic cases demonstrating earlier return of bowel function, reduced requirements for narcotics and equivalent complication rates. 45 The same author, using a validated survey tool to address functional outcomes including sexual dysfunction, cosmesis and quality of life, found comparable outcomes in both groups.…”

Section: Does Laparoscopic Colectomy Increase the Risk Of Desmoid Dismentioning

confidence: 99%

Dispelling misconceptions in the management of familial adenomatous polyposis

Chittleborough

Warrier

Heriot

et al. 2017

ANZ Journal of Surgery

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Patients with familial adenomatous polyposis require surgical intervention at some point in their lives. The diagnosis is often apparent from their phenotype and family history, however, this is not always the case. Many factors can influence the surgical strategy although the polyposis burden and distribution remain the main consideration. While prophylactic removal of the rectum and colon is often required, sparing the rectum at the index surgery is safe in select patients. This article aims to dispel misconceptions in the diagnosis and treatment of patients with familial adenomatous polyposis.

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Laparoscopic colectomy and restorative proctocolectomy for familial adenomatous polyposis

Abstract: Laparoscopic prophylactic treatment of FAP appears to be safe and feasible and may be an appealing alternative to open surgery. If the goal of prophylactic FAP surgery is to avoid cancer occurrence, laparoscopic surgery could be an important advancement.

Cited by 34 publications

References 48 publications

Gastrointestinal tract carcinoma in pediatric and adolescent age: The Italian TREP project experience

Gastrointestinal tract carcinoma in pediatric and adolescent age: The Italian TREP project experience

Colorectal polyps and polyposis syndromes

Dispelling misconceptions in the management of familial adenomatous polyposis

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