“…Since the NIH consensus conference on gallstones and laparoscopic cholecystectomy in 1992 suggested that patients with cirrhosis were ''not usually candidates for laparoscopic cholecystectomy'' [1] studies continue to be published supporting the safety of the approach in patients with Child's A or B cirrhosis (including downgrading from C after appropriate treatment) [39] with almost no data using the Model for EndStage Liver Disease (MELD) score to compare patients [139]; though there is little published data for Child's C patients, what is available suggests it should be avoided in favor of nonoperative approaches such as percutaneous cholecystostomy [140]. Recent studies generally agree that laparoscopic cholecystectomy in selected cirrhotics has a relatively low conversion rate (0-11%), complication rate (9.5-21%), and risk of dying (0-6.3%), with most showing worsening liver failure, including the presence of ascites and coagulopathy, predicting poorer outcomes [139][140][141][142][143][144]; a recent prospective randomized trial found that laparoscopic cholecystectomy was safer than open cholecystectomy in cirrhotics [145]. Some authors have suggested laparoscopic subtotal cholecystectomy as an alternative to laparoscopic cholecystectomy [146,147].…”