Single-port or single-incision laparoscopic surgery has been reported for a number of surgical procedures, including cholecystectomy, appendicectomy, and urological procedures. Single-port thoracoscopic procedures for evacuation of empyema have been described. However, to the authors' knowledge, there has been no report of single-port laparoscopic drainage of abdominal infected fluid collections, especially in children, in the relevant world literature. The authors report the first use of single-port laparoscopy with the TriPort system for drainage of abdominal infected fluid collections in children using the previous open appendicectomy wound. This approach was successfully completed in 2 consecutive children without conversion to open surgery. The operative duration was less than 30 minutes in each case. Both patients had no intraoperative or postoperative complications on follow-up at 8 weeks. Single-port laparoscopy with the TriPort system is safe and technically feasible for the management of pelvic collection and/or abscesses. Also, this technique is useful in multiloculated collections and allows for a washout of the peritoneal cavity at the same time, which is not the case for image-guided drainage. In addition, it also allows checking for the blowout of the appendicectomy stump as the cause for the collection. Finally, it has the advantage of reduced wound morbidity and better cosmesis.