Lanthanum-strontium manganites for magnetic nanohyperthermia: Fine tuning of parameters by substitutions in lanthanum sublattice

Shlapa, Yuliia; Solopan, Sergii; Боднарук, А.В.; Kulyk, M. M.; Каліта, В. М.; Tykhonenko-Polishchuk, Yulia; Tovstolytkin, A. I.; Зінченко, Віктор; Belous, A. G.

doi:10.1016/j.jallcom.2017.01.222

Cited by 23 publications

(12 citation statements)

References 32 publications

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“…According to XRD investigations, all samples are single-phase and crystallize in the distorted perovskite structure. The average nanoparticle sizes lie in the range 25-35 nm for the Fe-substituted series [17] and 31-38 nm for the Sm-substituted one [18].…”

Section: Resultsmentioning

confidence: 98%

“…Magnetic properties of the samples of both series were reported in Refs. [17,18]. It was shown that both kinds of substitutions (Mn → Fe and La → Sm) give rise to the decrease of room-temperature magnetization and the Curie temperature T C .…”

Section: Resultsmentioning

confidence: 99%

“…On the contrary, Sm substitution for La does not affect the quantity and oxidation state of Mn ions. Instead, it weakens inter-ionic interactions by means of introduction and subsequent enhancement of local distortions of crystalline structure [15,22], because the ionic radius of Sm 3+ is smaller than that of La 3+ [18].…”

Section: Resultsmentioning

confidence: 99%

“…Iron-and samarium-substituted manganite nanoparticles, La 0.77 Sr 0.23 Mn 1−x Fe x O 3 with x F e = 0, 0.02, 0.04, 0.06, and La 0.7−x Sm x Sr 0.3 MnO 3 with x Sm = 0, 0.01, 0.04, 0.06, 0.08, respectively, were synthesized via solgel method [17,18]. Water-soluble salts La(NO 3 ) 3 , Sm(NO 3 ) 3 , Sr(NO 3 ) 2 , Mn(NO 3 ) 2 and Fe(NO 3 ) 3 were used as starting reagents.…”

Section: Methodsmentioning

confidence: 99%

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Manganite Nanoparticles as Promising Heat Mediators for Magnetic Hyperthermia: Comparison of Different Chemical Substitutions

Tovstolytkin

Shlapa²,

Solopan³

et al. 2018

Acta Phys. Pol. A

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Magnetostatic properties and AC magnetic heating characteristics of (La,Sr)MnO3 nanoparticles with substitutions in manganese and lanthanum sublattices have been studied. The nanoparticles with average sizes in the range 25-38 nm were synthesized via sol-gel method. Fe substitution for Mn, as well as Sm substitution for La have been used in the experiment. It is shown that the increase in substitution level (for both Fe and Sm substitutions) results in lowering the Curie temperature TC and weakening heating efficiency under the action of AC magnetic field. The results demonstrate that the action of AC field causes effective heating of nanoparticles at temperatures lower than TC, while heating efficiency becomes strongly reduced at higher temperatures. It is proved experimentally that the substitutions in Mn sublattice result in more rapid changes of magnetic properties, as compared to the substitutions in La one. Thus, complex substitutions based on suitable combinations of substituting elements may serve as an efficient tool to "softly" tune the maximal temperature achieved during the AC magnetic field induced heating of nanoparticles, which is important for application of these materials as heat mediators for self-controlled magnetic nanohyperthermia.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Manganite Nanoparticles as Promising Heat Mediators for Magnetic Hyperthermia: Comparison of Different Chemical Substitutions

Tovstolytkin

Shlapa²,

Solopan³

et al. 2018

Acta Phys. Pol. A

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“…The realization of this scenario corresponds to an ideal therapy, and thus complete body magnetic fluid hyperthermia cancer therapy is intensively investigated by previous studies as an option in new cancer treatments to replace surgery, radiation therapy, and chemotherapy [1][2][3][4][5][6][7][8]. However, the selective annihilation of cancer cells, leaving the normal cells safe, is debatable since normal tissues are also warmed up due to eddy current loss.…”

Section: Introductionmentioning

confidence: 99%

Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment

Mamiya

Takeda

Naka

et al. 2017

Journal of Nanomaterials

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Magnetic fluid hyperthermia therapy is considered as a promising treatment for cancers including unidentifiable metastatic cancers that are scattered across the whole body. However, a recent study on heat transfer simulated on a human body model showed a serious side effect: occurrences of hot spots in normal tissues due to eddy current loss induced by variation in the irradiated magnetic field. The indicated allowable upper limit of field amplitude ac for constant irradiation over the entire human body corresponded to approximately 100 Oe at a frequency of 25 kHz. The limit corresponds to the value ac of 2.5 × 10 6 Oe⋅s −1 and is significantly lower than the conventionally accepted criteria of 6 × 10 7 Oe⋅s −1 . The present study involved evaluating maximum performance of conventional magnetic fluid hyperthermia cancer therapy below the afore-mentioned limit, and this was followed by discussing alternative methods not bound by standard frameworks by considering steady heat flow from equilibrium responses of stable nanoparticles. Consequently, the clarified potentials of quasi-stable core-shell nanoparticles, dynamic alignment of easy axes, and short pulse irradiation indicate that the whole-body magnetic fluid hyperthermia treatment is still a possible candidate for future cancer therapy.

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Nanoscale Heat Mediators for Magnetic Hyperthermia: Materials, Problems, and Prospects

Tovstolytkin

Белоус²,

Lytvynenko

et al. 2021

Surfaces and Interfaces of Metal Oxide Thin Films, Multilayers, Nanoparticles and Nano-Composites

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Lanthanum-strontium manganites for magnetic nanohyperthermia: Fine tuning of parameters by substitutions in lanthanum sublattice

Cited by 23 publications

References 32 publications

Manganite Nanoparticles as Promising Heat Mediators for Magnetic Hyperthermia: Comparison of Different Chemical Substitutions

Manganite Nanoparticles as Promising Heat Mediators for Magnetic Hyperthermia: Comparison of Different Chemical Substitutions

Practical Solution for Effective Whole-Body Magnetic Fluid Hyperthermia Treatment

Nanoscale Heat Mediators for Magnetic Hyperthermia: Materials, Problems, and Prospects

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