Langzeitergebnisse nach Handgelenkdenervation bei fortgeschrittenem karpalem Kollaps (SLAC-/SNAC-Wrist Stadium II und III)

Rothe, M.; Rudolf, Klaus-Dieter; Partecke, B.-D.

doi:10.1055/s-2006-924408

Cited by 50 publications

(10 citation statements)

References 4 publications

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“…1 ) oft nur die vollständige Versteifung des Handgelenkes als Therapieoption [ 1 -15 ] . Es ist richtig, dass die Handgelenkdenervation in solchen Fällen durchaus zu einer befriedigenden Schmerzreduktion führen kann, ohne dass die Beweglichkeit geopfert werden muss [ 7 ] . Bleibt jedoch die erhoff te Schmerzreduktion nach der Handgelenkdenervation aus oder ist sie nur von kurzer Dauer, so kann doch eine Komplettversteifung notwendig werden.…”

Section: Einleitung ▼unclassified

Die Resektion der proximalen Handwurzelreihe mit Ersatz des Kapitatum-Pols durch eine Pyrocarbonkappe (RCPI) beim fortgeschrittenen karpalen Kollaps

Szalay

Stigler

Kraus

et al. 2011

Handchir Mikrochir plast Chir

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The results of 5 patients suffering from advanced carpal collapse after proximal row carpectomy and replacement of the proximal pole of the capitate by means of a pyrocarbon cap are presented.5 patients with an average age of 40.2 years (23-66 years) suffering from advanced carpal collapse were treated by means of proximal row carpectomy and replacement of the proximal pole of the capitate between January 2005 and August 2008. Clinical and radiological follow-ups within an average post-operative period of 54.4 months (25-68 months) were conducted. For the assessment of the outcome the DASH score and the traditional Krimmer score were used.At the follow-up all patients were fully recovered and could expose the wrist to higher exertions. Radiologically the implants in 3 of 5 patients were found to be tight and at the original post-operative location in comparison with the post-operative X-rays. In 2 of 5 patients a mild seam of loosening was detected around the implant. In the traditional Krimmer score the patients reached 81 points (75-85 points) and in the DASH score 8 points (2.5-23.33 points).The described results of the present procedure define it as an alternative in treating patients suffering from advanced carpal collapse as far as evidence from this small collective can be considered. The small seam of loosening around implants in 2 of 5 patients suggests that we may expect further loosening of implants in the long run. Larger patient collectives are necessary to confirm these provisional results.

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Section: Einleitung ▼unclassified

Die Resektion der proximalen Handwurzelreihe mit Ersatz des Kapitatum-Pols durch eine Pyrocarbonkappe (RCPI) beim fortgeschrittenen karpalen Kollaps

Szalay

Stigler

Kraus

et al. 2011

Handchir Mikrochir plast Chir

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“…Die Anzahl der Patienten und der Nachuntersuchungszeitraum sind mit unseren Zahlen zu vergleichen. Das Patientenkollektiv setzt sich jedoch ausschlie ß lich aus Patienten mit einer SLAC -/ SNAC-wrist im Stadium II und III zusammen [19] . Ein wichtiges Ziel unserer Studie war es, die unterschiedlichen Pathologien des chronischen Handgelenksschmerz und das damit verbundene Patientenkollektiv mit zu ber ü cksichtigen.…”

Section: Diskussion ▼unclassified

Funktionelle Ergebnisse nach Handgelenksdenervation

Radu¹,

Schachner²,

Tränkle³

et al. 2010

Handchir Mikrochir plast Chir

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A positive test denervation is not a warranty for postoperative pain reduction after denervation of the wrist. Patients without arthrotic changes of the wrist benefit more from denervation than patients with arthrotic changes. Since the majority of patients with arthrotic changes still profited from a denervation we think of the operation as a valid alternative, since it leaves the possibility open for other, more difficult treatment options such as partial or total wrist fusion.

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“…Palliative wrist denervation is usually the first step of treatment due to its lesser consequences on wrist mobility. However, it is inefficient in a quarter to more than a third of cases [6,7]. The other surgical alternatives are: first row carpectomy, total or partial wrist arthrodesis and sometimes prosthesis wrist arthroplasty.…”

Section: Introductionmentioning

confidence: 99%

Development of Autologous Platelet-Rich Plasma Mixed-Microfat as an Advanced Therapy Medicinal Product for Intra-Articular Injection of Radio-Carpal Osteoarthritis: From Validation Data to Preliminary Clinical Results

Mayoly

Iniesta

Curvale

et al. 2019

IJMS

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Wrist osteoarthritis (OA) is one of the most common conditions encountered by hand surgeons with limited efficacy of non-surgical treatments. The purpose of this study is to describe the Platelet-Rich Plasma (PRP) mixed-microfat biological characteristics of an experimental Advanced Therapy Medicinal Product (ATMP) needed for clinical trial authorization and describe the clinical results obtained from our first three patients 12 months after treatment (NCT03164122). Biological characterization of microfat, PRP and mixture were analysed in vitro according to validated methods. Patients with stage four OA according to the Kellgren Lawrence classification, with failure to conservative treatment and a persistent daily painful condition >40 mm according to the visual analog scale (VAS) were treated. Microfat-PRP ATMP is a product with high platelet purity, conserved viability of stromal vascular fraction cells, chondrogenic differentiation capacity in vitro and high secretion of IL-1Ra anti-inflammatory cytokine. For patients, the only side effect was pain at the adipose tissue harvesting sites. Potential efficacy was observed with a pain decrease of over 50% (per VAS score) and the achievement of minimal clinically important differences for DASH and PRWE functional scores at one year in all three patients. Microfat-PRP ATMP presented a good safety profile after an injection in wrist OA. Efficacy trials are necessary to assess whether this innovative strategy could delay the necessity to perform non-conservative surgery.

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Langzeitergebnisse nach Handgelenkdenervation bei fortgeschrittenem karpalem Kollaps (SLAC-/SNAC-Wrist Stadium II und III)

Cited by 50 publications

References 4 publications

Die Resektion der proximalen Handwurzelreihe mit Ersatz des Kapitatum-Pols durch eine Pyrocarbonkappe (RCPI) beim fortgeschrittenen karpalen Kollaps

Die Resektion der proximalen Handwurzelreihe mit Ersatz des Kapitatum-Pols durch eine Pyrocarbonkappe (RCPI) beim fortgeschrittenen karpalen Kollaps

Funktionelle Ergebnisse nach Handgelenksdenervation

Development of Autologous Platelet-Rich Plasma Mixed-Microfat as an Advanced Therapy Medicinal Product for Intra-Articular Injection of Radio-Carpal Osteoarthritis: From Validation Data to Preliminary Clinical Results

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