Language Function After Temporal Lobectomy Without Stimulation Mapping of Cortical Function

Davies, Keith G.; Maxwell, Robert E.; Beniak, Thomas E.; Destafney, Elizabeth; Fiol, Miguel

doi:10.1111/j.1528-1157.1995.tb00971.x

Cited by 58 publications

(23 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For instance, several authors have claimed that a nontailored left anterior temporal lobectomy without the use of ESM does not worsen language functions. 14,31 This conflicts with the results of ESM studies in similar groups of patients with epilepsy where, in approximately 20% of patients, language areas are found in the dominant anterior temporal lobe. 63 Similar conflicting observations have been made for the basal temporal language area.…”

Section: Electrocortical Stimulation Mappingcontrasting

confidence: 53%

The role of functional magnetic resonance imaging in brain surgery

Rutten

Ramsey

2010

FOC

View full text Add to dashboard Cite

New functional neuroimaging techniques are changing our understanding of the human brain, and there is now convincing evidence to move away from the classic and clinical static concepts of functional topography. In a modern neurocognitive view, functions are thought to be represented in dynamic large-scale networks. The authors review the current (limited) role of functional MR imaging in brain surgery and the possibilities of new functional MR imaging techniques for research and neurosurgical practice. A critique of current clinical gold standard techniques (electrocortical stimulation and the Wada test) is given.

show abstract

Section: Electrocortical Stimulation Mappingcontrasting

confidence: 53%

The role of functional magnetic resonance imaging in brain surgery

Rutten

Ramsey

2010

FOC

View full text Add to dashboard Cite

show abstract

“…Nevertheless, some clinical studies attest to a role for the right anterior temporal lobe in semantic processing (Lambon-Ralph et al, 2001), although neural reorganization in response to acute or progressive focal cortical damage may render the functional anatomy in patients quite different from that in normal subjects. This qualification also applies to the major argument advanced against roles for the lateral TP and the anterior FG in language comprehension; namely, the absence of a significant language deficit after anterior temporal lobectomy (ATL) for intractable temporal lobe epilepsy (TLE) (Hermann and Wyler, 1988;Davies et al, 1995). However, abnormal electrical activity, both ictal and interictal, is linked to reorganization of language cortex in TLE (Janszky et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Converging Language Streams in the Human Temporal Lobe

et al. 2006

View full text Add to dashboard Cite

There is general agreement that, after initial processing in unimodal sensory cortex, the processing pathways for spoken and written language converge to access verbal meaning. However, the existing literature provides conflicting accounts of the cortical location of this convergence. Most aphasic stroke studies localize verbal comprehension to posterior temporal and inferior parietal cortex (Wernicke's area), whereas evidence from focal cortical neurodegenerative syndromes instead implicates anterior temporal cortex. Previous functional imaging studies in normal subjects have failed to reconcile these opposing positions. Using a functional imaging paradigm in normal subjects that used spoken and written narratives and multiple baselines, we demonstrated common activation during implicit comprehension of spoken and written language in inferior and lateral regions of the left anterior temporal cortex and at the junction of temporal, occipital, and parietal cortex. These results indicate that verbal comprehension uses unimodal processing streams that converge in both anterior and posterior heteromodal cortical regions in the left temporal lobe.

show abstract

“…In terms of recovery from brain injury, activity within anterior and posterior and left and right temporal cortical areas may be compensatory. Thus, transcortical sensory aphasia after a left temporoparietal stroke is usually transient (Berthier, 1999), and a left anterior temporal lobectomy performed to alleviate intractable temporal lobe seizures has a relatively minor impact on language (Hermann and Wyler, 1988;Davies et al, 1995). In contrast, in semantic dementia, the loss of semantic knowledge becomes most evident when both left and right anterior temporal cortex are atrophic (Lambon-Ralph et al, 2001;Nestor et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

A Common System for the Comprehension and Production of Narrative Speech

Awad

Warren²,

Scott³

et al. 2007

J. Neurosci.

131

104

View full text Add to dashboard Cite

Humans devote much time to the exchange of memories within the context of shared general and personal semantic knowledge. Our hypothesis was that functional imaging in normal subjects would demonstrate the convergence of speech comprehension and production on high-order heteromodal and amodal cortical areas implicated in declarative memory functions. Activity independent of speech phase (that is, comprehension and production) was most evident in the left and right lateral anterior temporal cortex. Significant activity was also observed in the posterior cortex, ventral to the angular gyri. The left and right hippocampus and adjacent inferior temporal cortex were active during speech comprehension, compatible with mnemonic encoding of narrative information, but activity was significantly less during the overt memory retrieval associated with speech production. Therefore, although clinical studies suggest that hippocampal function is necessary for the retrieval as well as the encoding of memories, the former appears to depend on much less net synaptic activity. In contrast, the retrosplenial/posterior cingulate cortex and the parahippocampal area, which are closely associated anatomically with the hippocampus, were equally active during both speech comprehension and production. The results demonstrate why a severe and persistent inability both to understand and produce meaningful speech in the absence of an impairment to process linguistic forms is usually only observed after bilateral, and particularly anterior, destruction of the temporal lobes, and emphasize the importance of retrosplenial/posterior cingulate cortex, an area known to be affected early in the course of Alzheimer's disease, in the processing of memories during communication.

show abstract

Language Function After Temporal Lobectomy Without Stimulation Mapping of Cortical Function

Cited by 58 publications

References 28 publications

The role of functional magnetic resonance imaging in brain surgery

The role of functional magnetic resonance imaging in brain surgery

Converging Language Streams in the Human Temporal Lobe

A Common System for the Comprehension and Production of Narrative Speech

Contact Info

Product

Resources

About