“…The first proposal to use amines as a method to encourage carbohydrate digestion in the ruminant was made more than a century ago (Zuntz, 1891) and later examined and verified as an effective NPN supplementation strategy (Hart, Bohstedt, Deobald, & Wegner, 1939). Attempts to manage the N release rate of dietary urea in the rumen with other forms of NPN (Bergner, Görsch, Wiesner, & Willer, 1977) suggests that N supply to the rumen may have been through rumeno-hepatic circulation, as proposed earlier (Egan & Moir, 1965). Additional studies described the effects of short-term duodenal infusion of urea in sheep fed low-protein, high-forage diets, showing improvements in feed intake and digestibility as well as improved N balance (Egan, 1965;Egan & Moir, 1965).…”