Langerhans cell histiocytosis in adultsReport from the International Registry of the Histiocyte Society

Erdheim-Chester disease and pituitary involvement: a unique case and the literature

“…Secondly, his polyuria and polydipsia improved and he became not to need DDAVP three months after the treatment with interferon α. It is known that CDI does not tend to ameliorate even if primary disease such as inflammation [4], infiltration [5,6] or tumor [7,8], is successfully treated.…”

"A Study of Adult Onset Generalized Eruptive Langerhans Cell Histiocytosis with Rare Association of Nail Pterygium"

“…Most common presenting symptoms were local pain(34%), particularly due to bone involvement, weight loss (11%), and fever (10%). Lung was the most frequently involved organ system followed by bone and then the skin (3) .…”

“…The clinical course and prognosis of LCH is diverse which ranges from a spontaneously regressing single lesion to a life-threatening multisystem disease with rapid progression and sometimes even death. In adults, lungs are the most commonly involved system followed by bones and skin (2,3) . Cutaneous lesions in LCH can be the great pretender and mimics number of common dermatoses (4) it creates more confusion when it is the presenting feature , which is rarely seen in adults.…”

Thigh Pain in an 18-year-old Man

“…The true incidence of this condition is unknown as many instances of this disease are asymptomatic and thus not treated and confirmed with a histologic diagnosis. A male predominance has been described in some case series [1,12]. The incidence seems to be higher in people of northern European descent than in people of African or Asian descent [13].…”