Langerhans cell histiocytosis (histiocytosis x) – in the mandible

Abstract

<p>This article reports a case of 65 year-old man consultedin a private radiology dental clinic for a panoramicradiography, where was indicated a radiolucent area,extending into the periapical region of the teeth 35 to 43 to the base of the mandible. Radiographydiagnosis was difficult. The immunohistochemical examination showed immunoreactivity for theproteins CD 68, S-100 and CD 1a. Histopathologicaldiagnosis was obtained for Langerhans cell granuloma(histiocytosis X). Langerhans cell histiocytosis iscaused by the abnormal proliferation of histiocytes, previously called Histiocytosis X. It is a rare diseasethat preferentially affects children and young adultswith a predilection for males and can affect differentparts of the body.</p><p>Keywords<br />Adult; Histiocytosis; Langerhans; Mandible.</p>