Landscape ecology and urban biodiversity in tropical Indonesian cities

Arifin, Hadi Susilo; Nakagoshi, Nobukazu

doi:10.1007/s11355-010-0145-9

Cited by 82 publications

(28 citation statements)

References 12 publications

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“…Moreover, we also deployed the Indonesian natural product compounds for virtual screening purpose to find the suitable lead compounds for combating Ebola. The reason for choosing the Indonesian natural product compounds because of Indonesia, as one of the largest megadiversity countries, has no less than 38,000 flowering plants that grow around the nation, with 55% of them are endemic plants [51,52].…”

Section: Our In Silico Methodsmentioning

confidence: 99%

Bioinformatics Approach to Screening and Developing Drug against Ebola

Tambunan¹,

Alkaff²,

Nasution³

2018

Advances in Ebola Control

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Ebola is an acute disease causing hemorrhagic fever marked with high mortality rate. The patients who suffer from Ebola only receive palliative care because there is no available drug which can consistently cure this disease. To date, no cure has been found to treat this disease. Bioinformatics and computer-aided drug discovery and development (CADDD) are employed to utilize the readily available genomic and proteomic data and enhance the hit rate of the novel and repurposed drug for Ebola therapy. Additionally, the time and cost of wet laboratory experiments can be drastically reduced by the support of bioinformatics approach. Our laboratory has succeeded not only in creating the bioinformatics research pipeline but also screening and developing the drug candidate to cure Ebola. Through pharmacophore-based virtual screening and molecular docking simulations, we discovered that about three Indonesian natural product compounds have noteworthy molecular interactions against EBOV VP35 protein, which are responsible for the RNA synthesis of the Ebola. These compounds can be reevaluated further through advances in in silico simulation and in vitro experiments.

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Section: Our In Silico Methodsmentioning

confidence: 99%

Bioinformatics Approach to Screening and Developing Drug against Ebola

Tambunan¹,

Alkaff²,

Nasution³

2018

Advances in Ebola Control

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“…Interestingly, the effects of roadsides and wetland detention basins relative to conventional counterparts were infrequently studied when compared to other GI types despite their high frequency and importance in urban environments. Road ecology has been a field of study for several decades and previously research has highlighted that when managed, can be rich in both native and planted species (Arenas, Escudero, Mola, & Casado, 2017;Arifin & Nakagoshi, 2011). Further exploration of the potential to vegetate roadsides could have significant effects on biodiversity because of the large area they occupy in cities and high degree of connectivity roadways share to natural habitat or other GI types (von der Lippe & Kowarik, 2008).…”

Section: Gi Type and Taxa-specific Considerationsmentioning

confidence: 99%

The contribution of constructed green infrastructure to urban biodiversity: A synthesis and meta‐analysis

Filazzola

Shrestha

MacIvor

2019

Journal of Applied Ecology

125

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The development of buildings and other infrastructure in cities is viewed as a threat to local biodiversity and ecosystem functioning because natural habitat is replaced. However, there is momentum for implementing green infrastructure (GI), such as green roofs, wetland detention basins and community gardens, that partially offset these impacts and that benefit human health. GI is often designed to explicitly support ecosystem services, including implied benefits to biodiversity. The effects of GI on biodiversity have been rarely quantified, but research on this topic has increased exponentially in the last decade and a synthesis of the literature is needed. Here, we examined 1,883 published manuscripts and conducted a meta‐analysis on 33 studies that were relevant. We determined whether GI provides additional benefits to biodiversity over conventional infrastructure or natural counterparts. We also highlighted research gaps and identified opportunities to improve future applications. We determined that GI significantly improves biodiversity over conventional infrastructure equivalents, and that in some cases GI had comparable measures of biodiversity to natural counterparts. Many studies were omitted from these analyses because we found GI research has generally neglected conventional experimental design frameworks, including controls, replication or adequate sampling effort. Synthesis and applications. Our synthesis identified that taxa specificity is an important consideration for green infrastructure (GI) design relative to the more common measurements at the community level. We also identified that ignoring multi‐trophic interactions and landscape‐level patterns can limit our understanding of GI effects on biodiversity. We recommend further examination of species‐specific differences among infrastructures (i.e. green, conventional or natural equivalents) or using functional traits to improve the efficacy of GI implementation on urban biodiversity. Furthermore, we encourage policy makers and practitioners to improve the design of GI to benefit urban ecosystems because of the potential benefits for both humans and global biodiversity.

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“…Improved management is essential to retain resilience in the face of global climate change and ongoing urban development pressures and to build a sustainable city. The Indonesian government has ratified a law to ensure that cities retain a minimum area of 30% green open space to provide for these important ecological services (Arifin and Nakagoshi 2011). Good management of natural open spaces will unlock indirect job opportunities in the tourism sector and enable potential economic spin-offs and social well-being.…”

Section: Threats To Cape Town's Biodiversitymentioning

confidence: 99%

Can Cape Town's unique biodiversity be saved? Balancing conservation imperatives and development needs

Holmes¹,

Rebelo²,

Dorse³

et al. 2012

E&S

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ABSTRACT. Cape Town is an urban hotspot within the Cape Floristic Region global biodiversity hotspot. This city of 2,460 km² encompasses four local centers of fynbos plant endemism, 19 national terrestrial vegetation types (six endemic to the city), wetland and coastal ecosystems, and 190 endemic plant species. Biodiversity in the lowlands is under threat of extinction as a result of habitat loss to agriculture, urban development, mining, and degradation by invasive alien plants. Cape Town's population is 3.7 million, increasing by an estimated 55,000 people/yr, which puts pressure on biodiversity remnants for development. South Africa is a signatory to international instruments to reduce biodiversity loss and has a good legislative and policy framework to conserve biodiversity, yet implementation actions are slow, with limited national and provincial support to conserve Cape Town's unique and irreplaceable biodiversity. The lack-of-action problem is two-fold: national government is slow to implement the policies developed to realize the international instruments it has signed, with conservation initiatives inadequately funded; and local governments are not yet recognized as important implementation partners. A further problem is created by conflicting policies such as the national housing policy that contributes to urban sprawl and loss of critical biodiversity areas. The City's Biodiversity Management Branch, with partners, is making some headway at implementation, but stronger political commitment is needed at all levels of government. Our objective is to improve the status and management of biodiversity in existing conservation areas through the statutory proclamation process and management effectiveness monitoring, respectively, and to secure priority areas of the BioNet, Cape Town's systematic biodiversity plan. The most important tools for the latter are incorporating the BioNet plan into City spatial plans; communication, education, and public awareness; negotiating appropriate management of public land; and conservation stewardship on private land. The timeframe to save Cape Town's biodiversity is short, and it is unlikely that full success will be achieved without national or international funding and political will at all levels of government.

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Landscape ecology and urban biodiversity in tropical Indonesian cities

Cited by 82 publications

References 12 publications

Bioinformatics Approach to Screening and Developing Drug against Ebola

Bioinformatics Approach to Screening and Developing Drug against Ebola

The contribution of constructed green infrastructure to urban biodiversity: A synthesis and meta‐analysis

Can Cape Town's unique biodiversity be saved? Balancing conservation imperatives and development needs

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